我院2011-2013年抗帕金森病药使用分析  

Analysis of the Utilization of Anti-Parkinson's Disease Drugs in Our Hospital during 2011-2013

作　　者：奚月芬[1] 

机构地区：[1]江苏省原子医学研究所附属江苏省江原医院,江苏无锡214063

出　　处：《中国药房》2014年第46期4333-4335,共3页China Pharmacy

摘　　要：目的:了解我院抗帕金森病(PD)药的使用情况,为临床合理用药提供参考。方法:收集我院2011-2013年每年11-12月诊断为PD的所有门诊处方共计1 526张,从中随机抽取450张,收集患者的性别、年龄、用药情况等信息资料,对不同年龄段患者用药情况进行统计分析。同时以我院2011-2013年抗PD药的使用记录为依据,采用回顾性调查方法,对抗PD药的年销售金额、各品种销售金额排序、用药频度(DDDs)、日均费用(DDC)等进行统计、分析。结果:普拉克索在年轻患者中的使用率较高,销售金额和DDDs增长最快,年销售金额所占比例增长幅度最大;而复方左旋多巴年销售金额所占比例逐年下降。DDDs排名靠前的分别为金刚烷胺、苯海索,且其DDC均较低。随着患者年龄的增长,加用复方左旋多巴的处方比例逐渐增加。结论:我院PD治疗方案较合理,但由于PD患者经济负担较重,在药物选择上需要根据患者病情的特点、年龄、职业、经济状况等因素综合考虑,从中选择合适的药物。OBJECTIVE： To investigate the use of anti-Parkinson＇s disease （PD） drugs in our hospital so as to provide refer- ence for rational use of drugs in the clinic. METHODS： 450 prescriptions were randomly collected from 1 526 outpatient prescrip- tions of PD in our hospital during 2011 and 2013. The gender, age, medication and other information were collected and the medi- cation of different age groups were analyzed statistically. By retrospective study, the utilization of anti-PD drugs in our hospital dur- ing 2011- 2013 were analyzed statistically in respects of annual consumption sum, consumption sum ratio, DDDs, DDC, etc. RE- SULTS： Pramipexole was used more frequently in younger patients. The consumption sum and DDDs of pramipexole increased fast- est, and the proportion of annual consumption sum increased fastest; while that of Compound levodopa decreased year by year. DDDs of amantadine and benzhexol took up the first 2 places, while the DDC of them were lower. With increasing of patient＇ s age, the proportion of Compound levodopa prescriptions was gradually increased. CONCLUSIONS： The PD treatment scheme in our hospital is reasonable. Due to heavy economic burden of PD patients, appropriate anti-PD drugs should be chosen by consider- ing about the characteristics of disease, age, occupation and economic status, in order to improve the life quality of patients.

关 键 词：抗帕金森病药 使用情况 用药频度 日均费用 

分 类 号：R971.5[医药卫生—药品] R969.3[医药卫生—药学]