针灸治疗绝经后骨质疏松症临床文献的系统评价  

Systematic review of literatures of acupuncture and moxibustion for treatment of postmenopausal osteoporosis(PMO)

作　　者：李胜[1] 张丰正[1] 王鸿度[1] 江洋[1] 潘小燕[1] 

机构地区：[1]泸州医学院中西医结合学院针灸教研室

出　　处：《泸州医学院学报》2014年第5期461-467,共7页Journal of Luzhou Medical College

基　　金：国家自然科学基金:电针是少阳经穴对大鼠骨重塑偶联的"和调"机制(81241108)

摘　　要：目的:评价关于治疗绝经后骨质疏松症针刺疗法和药物疗法。方法:以针刺、针灸、绝经后骨质疏松等为主题词,检索了国内相关医学数据库CNKI、万方、维普等关于针灸治疗绝经后骨质疏松症的临床对照试验,治疗组以针刺治疗为主,对照组以药物治疗为主,以骨质疏松症总有效率和骨密度改变为测量指标。对纳入的研究进行方法学质量评价之后,采用Rev Man5.1进行Meta分析。结果:共纳入31篇文献,并对其中9篇文献采用Rev Man 5.1进行Meta分析,其中试验组365例,对照组252例。其中4个研究总有效率合并RR=1.38,95%CI为[1.15,1.65]。Z=3.51,P=0.0004,显示针灸疗法对绝经后骨质疏松治疗的总有效率优于药物组,差异有统计学意义;6个研究治疗后骨密度值改变合并WMD=0.06,95%CI[0.02,0.10],Z=2.91,P<0.05,显示针灸疗法在改善绝经后骨质疏松骨密度上较药物疗法有优势,差异有统计学意义。结论:从纳入的国内文献来看,针刺治疗骨质疏松症有效,但是需要更多的高质量文章来证实。Objective： To assess the effectiveness of acupuncture and moxibustion therapy and drug therapy for PMO. Methods：Acupuncture, moxibustion, PMO, etc. were selected as the theme words to retrieve the related medical data base at home, such as CNKI、VIP、Wan fang etc. and clinically randomized controlled trials were used as enrolled criteria and the treatment group was mainly treated with acupuncture, and the control group with medicine. The total effective rate and BMD changed values were used as assessment indexes. After the methodological quality assessment, all studies were conducted for Meta-analysis by Rev Man-5.1. Results：Altogether 31 studies were enrolled.Among them 9 studies were conducted for Meta-analysis, treatment group（365 cases, control group 252 cases）.The total RR of the total effective rate in 4 studies was 1.38 with 95%CI[1.15,1.65];and the total WMD of the BMD changed values in 6 studies was 0.06 with 95%CI [0.02,0.10]. Each index in the acupuncture group on PMO was superior to that in the medicine group（P 0.05）. Conclusion：Acupuncture and moxibustion therapy for PMO is effective,but more high-quality studies are required to prove this viewpoint.

关 键 词：骨质疏松症 针刺疗法 系统评价 

分 类 号：R245[医药卫生—针灸推拿学] R242[医药卫生—中医临床基础]