中国人群食管癌发病影响因素的系统综述和Meta分析  

A Meta-analysis of influence factors on esophageal cancer in the Chinese population

作　　者：谭淼[1] 熊文婧[2] 朱宗玉 高露[1] 姜晶[1] 让蔚清[1] 

机构地区：[1]南华大学公共卫生学院流行病与卫生统计学系,湖南衡阳421001 [2]北京中医药大学循证医学中心,北京100029

出　　处：《现代预防医学》2014年第23期4310-4316,共7页Modern Preventive Medicine

基　　金：公共卫生与预防医学湖南省重点学科基金支持;南华大学"十二五"校级重点实验室疾病控制评价重点实验室项目基金支持

摘　　要：目的综合定量评价中国人群食管癌发病影响因素。方法全面检索国内相关文献,以CMA v2软件进行Meta分析。结果共纳入36篇文献,累计病例9 037例,对照11 599例;共有16个因素的合并OR值有显著意义。结论水果、豆制品是中国人群食管癌发病的保护因素;干硬食品、烟熏食品、吸烟史、油炸食品、进餐不定时、进食快、高盐食品、精神创伤史、酸醋食品、霉变食品、腌制食品是其危险因素。Objective To quantify the influence factors on esophageal cancer in Chinese population. Methods Relevant casecontrol studies on influence factors on esophageal cancer were gathered with Meta-analysis by CMA v2 after data abstraction.Results 36 articles were eligible for inclusion in the Meta-analysis, while the cumulative cases and controls were 9 037 and 11 599,respectively. The OR value（95%CI） of each influence factors were calculated, and sixteen of them were statistically significant.Conclusion Rough food, smudging food, smoking, fried food, irregular diet, quick eating, heavy-salty food, mental irritation, acid food, moldy food, preserved food are the risk factors of esophageal cancer in the Chinese population, while fruits and legume are protective factors.

关 键 词：食管癌 影响因素 系统综述 META分析 

分 类 号：R195.4[医药卫生—卫生统计学]