高原衰退症脑力衰退型中医证候特征分析研究  

Analysis of Syndromes Characteristics of Mental Type High Altitude Deterioration

作　　者：刘春[1] 蒋春华[1] 陈郁[1] 高伊星[1] 陈莉[1] 高钰琪[1] 

机构地区：[1]第三军医大学高原军事医学系

出　　处：《中医杂志》2014年第23期2025-2028,共4页Journal of Traditional Chinese Medicine

基　　金：军队中医药科研专项课题(2010ZYZ132)

摘　　要：目的探讨高原衰退症脑力衰退型的证候特点。方法对移居高原汉族青年进行调查诊断,将符合高原衰退症脑力衰退型诊断标准的患者187例设为高原衰退组,将高原研究对象中不符合高原衰退症诊断标准且血红蛋白(Hb)浓度<210 g/L,肺动脉平均压<25 mm Hg的31例纳入高原健康组,另在平原(海拔463 m)选取86名汉族健康青年为平原健康组。对高原衰退组患者辨证分为心脾两虚型、心肾不交型、肾阳虚损型。调查高原衰退组患者症状频率,测量各组受试者血液红细胞数、红细胞压积值,分析不同海拔高度及不同移居高原时间下各证型分布情况。结果 187例患者中心脾两虚型97例、心肾不交型51例、肾阳虚损型39例。中医辨证所涉及的31种症状中,前10种症状分别为健忘、爪甲青紫、唇青紫、注意力下降、失眠不寐、耳鸣、倦怠乏力、齿衄、心悸、头晕。高原衰退组中心脾两虚型、心肾不交型、肾阳虚损型患者红细胞计数与红细胞压积值均较平原健康组和高原健康组增高(P<0.05或P<0.01)。不同海拔高度各证型分布比较差异无统计学意义(P>0.05)。移居高原1年和2年的患者证型分布分别与移居高原3年以上的证型分布比较差异有统计学意义(P<0.01)。结论高原衰退症脑力衰退型以心、脾、肾三脏虚损为本,并有夹瘀特点,随着在高原地区生活时间的延长,病位逐渐转变为以肾为主。Objective To discuss syndrome characteristics of mental type high altitude deterioration. Methods We investigated and diagnosed on the plateau＇s migrated Han youths and set 187 patients who met the diagnosis of mental type high altitude deterioration into high altitude deterioration group, while 31 patients who didn＇t meet the diagnosis but with hemoglobin （Hb） concentration less than 210g/L, mean pulmonary artery pressure less than 25mmHg into high altitude healthy group. A total of 86 healthy Han youths who lived in the plain （ an altitude of 463m） was chosen into plain healthy group additionally. Syndrome differentiation of high altitude deterioration group suggested heart-spleen deficiency, heart-kidney disharmony and kidney yang deficiency. We studied the frequency of symptoms of high altitude deterioration group, tested red blood cells count and hematocrit of all groups, and analyzed distribution of different syndromes at different altitudes and migration time. Results In 187 patients, there are 97 cases of heart-spleen deficiency syndrome, 51 cases of heart-kidney disharmony, 39 cases of kidney yang deficiency. In the 24 symptoms mentioned by TCM syndrome differentiation, the top ten symptoms in frequency are obliviousness, cyanosis of nails, cyanosis of lips, decreased attention, insomnia, tinnitus, lack of appetite, fatigue, gum bleeding, palpitation, dizziness. In high altitude deterioration group, patients with the syndrome of heart-spleen deficiency, heart-kidney disharmony and kidney yang deficiency showed inceased red blood cells count and hematocrit comparing with those of plain healthy group and high altitude healthy group （ P 〈 0. 05 or P 〈 0.01 ）. Distribution of different syndromes at different altitudes suggests no significance statistically （ P 〉 0. 05 ）. The difference of syndrome distribu- tion in patients migrated to the plateau for 1 and 2 years and patients migrated to the plateau for more than 3 years was statistically significant （ P 〈 0. 01 ）. Conclusi

关 键 词：高原衰退症 脑力衰退型 中医证候 

分 类 号：R259[医药卫生—中西医结合]