肾衰方治疗慢性肾衰临床观察  

Clinical Observation of Shenshuai Decoction on Treating CRF

作　　者：叶玉妹 张晓丹 蔡艳 赵子玲 杨慰 陈杰 杨晓萍 

机构地区：[1]上海第七人民医院,上海200137

出　　处：《辽宁中医杂志》2014年第11期2343-2344,共2页Liaoning Journal of Traditional Chinese Medicine

基　　金：上海市传统医学示范中心建设项目

摘　　要：目的:观察中药肾衰方治疗慢性肾功能衰竭(CRF)的临床疗效。方法:将60例CRF患者,随机分为治疗组30例和对照组30例。两组均采用低盐、优质低蛋白饮食,根据病情选择降压、调节水、电解质、酸碱平衡等,并口服中药肾衰方加辨证治疗。观察两组治疗后临床疗效,观察治疗前后血尿素氮、血肌酐及血红蛋白水平的变化。结果:治疗组总有效率83.39%,对照组为46.67%,两组比较,差异有非常显著性意义(P<0.01)。治疗后治疗组血红蛋白较对照组升高明显,血肌酐、血尿素氮较对照组下降,差异均有非常显著性意义(P<0.01)。结论:从整体、多靶点、多融点、远期疗效证明解毒泄浊的肾衰方的优势,对慢性肾功能不全确实有效,从而探索延缓慢性肾衰进展的新途径。Objective：To observe the clinic effect of Shenshuai Decoction in treating chronic renal failure （CRF）. Methods：60 CRF patients be choosed to two groups, one was taken Shenshuai decoction as treatment group, and another was control group. Both selected food of high quality containing low salt and albumen, and choose to suppress the blood presure and adjust Water - elect - rolyte acid - base balance, etc. Observe the clinic effect before and after the treatment, and the changes in the level of blood urea nitrogen,blood creatinine and haemoglobin. Results ：The general effective rate of treatment group is 83.39% , the con- trol group is 46.67% ,which is signifigent diffrent （ P 〈 O. 01 ）. The increasing of Hemoglobin （Hb） of treatment group is higher than control group （P 〈 0. O1 ）, the decreasing of Scr and Bun of is higher than control group （ P 〈 O. 01 ）. Conclusion ： Thereby, the advantages of Shenshuai Decoction which can neutralize toxin and disperse turbidity were proved by its long - term effect by multiple target points and melting points in an all - round manner, and it was really effective to chronic renal insufficiency. On the basis,we can explore new approaches to retard the progress of CRF.

关 键 词：慢性肾功能不全 肾衰方 

分 类 号：R692.5[医药卫生—泌尿科学]