固相萃取–气相色谱–串联质谱法测定塑料食品包装材料中3种抗氧化剂的残留量  

Determination of Three Antioxidant Residues in Food Plastic Packaging Materials by Solid Phase Extraction–Gas Chromatography–Tandem Mass Spectrometry

作　　者：姚帮本[1] 王道俊[1] 储大勇[1] 

机构地区：[1]安徽省产品质量监督检验研究院,合肥230051

出　　处：《化学分析计量》2014年第6期20-24,共5页Chemical Analysis And Meterage

基　　金：国家质检总局科技计划项目(2014QK004);安徽省质量技术监督局科研专项项目(13zj370032)

摘　　要：建立了气相色谱-串联质谱法测定塑料食品包装材料中抗氧化剂二丁基羟基甲苯（BHT）、丁基羟基茴香醚（BHA）和特丁基对苯二酚（TBHQ）残留量的分析方法。样品采用环己炕-乙酸乙酯混合溶剂超声萃取，经固相萃取法富集和净化，采用气相色谱-串联质谱在多反应监测模式下进行测定。结果表明，3种抗氧化剂质量浓度在0．05～20mg／L范围内线性关系良好，线性相关系数大于0．999；BHT，BHA，TBHQ的检出限分别为0．005，0．01，0．03mg／kg；平均添加回收率为88．7％～104．0％；测定结果的相对标准偏差小于5．5％（n=6）。该方法操作简便，灵敏度高，重复性好，可用于塑料食品包装材料中抗氧化剂BHT，BHA，TBHQ残留量的测定。A new method for the simultaneous determination of three antioxidant residues （butylated hydroxytoluene, butylated hydroxyanisole, tertiary butylhydroquinone）in food plastic packaging materials by solid phase extraction-gas chromatography-tandem mass spectrometry（GC-MS / MS） was developed. The antioxidants were extracted from the samples with cyclohexane-ethyl acetate in the assistant of ultrasonic extraction, and then enriched and cleaned-up with solid phase extraction on a silica column. The detection was carried out by GC-MS / MS in the single-reaction monitoring （SRM） mode. The calibration curves showed good linearity in the range of 0.05-20 mg/L with the correlation coefficients more than 0.999. The detection limits were 0.005,0.01 and 0.03 mg/kg for BHT, BHA and TBHQ, respectively. The average recoveries of the three antioxidants in commercial food plastic packaging materials were 88.7%-104.0%, the relative standard deviations were less than 5.5%（n=6）. This method is simple, sensitive, highly reproducible, and suitable for determination of three antioxidant residues in food plastic packaging materials.

关 键 词：固相萃取 气相色谱-串联质谱法 抗氧化剂 塑料食品包装材料 

分 类 号：O657[理学—分析化学]