复发性流产患者抗精子抗体检测与分析  

Analysis of serum anti-sperm antibody in recurrent spontaneous abortion couples

作　　者：顾华妍[1] 任钧[1] 张海燕[1] 邓雨峰[1] 钱婧[1] 吕虹洁[1] 

机构地区：[1]重庆市妇幼保健院,重庆400010

出　　处：《中国优生与遗传杂志》2014年第11期104-105,共2页Chinese Journal of Birth Health & Heredity

摘　　要：目的探讨抗精子抗体在复发性流产患者孕前检查中的应用价值。方法选取420例有复发性流产史患者作为试验组,其中男189例,女231例,对其进行抗精子抗体检测;同时选取有正常生育史的45例男性与65例女性作为参照组,对两组的抗精子抗体的检测结果进行比较分析。结果试验组女性的阳性率为10.39%,男性的阳性率为7.26%,对照组女性的阳性率为1.54%,男性对照组中无人发现抗体阳性,RSA组的抗体阳性率明显高于正常对照组,差别有统计学意义(P<0.05)。结论 As Ab的产生与RSA密切相关,在对复发性流产患者的优生咨询中,需重视免疫学因素。Objectives：To investigate the levels of serum As Ab in recurrent spontaneous abortion couples and explore its clinical significance.Methods：Levels of serum As Ab in 530 people were detected by ELISA.Results：The rates of elevated serum As Ab in RSA period men and women were 7.26% and 10.39% respectively.The rates of elevated serum As Ab in ordinary fertile period women were 1.54%.Conclusion：As Ab might be associated with the recurrent spontaneous abortion.

关 键 词：复发性流产 抗精子抗体 孕前检查 

分 类 号：R714.21[医药卫生—妇产科学]