输尿管镜治疗中用应预防性抗生素的疗效分析  

Comparison of the Different Opportunity for Antibiotic Prophylaxis before Ureterscopic Holmium Laser Lithotripsy

作　　者：周睿[1] 朱劲松[1] 戴宇红[1] 陈志洁[1] 鲍彤[1] 杨凯[1] 

机构地区：[1]安徽医科大学附属安庆医院泌尿外科,安徽安庆246000

出　　处：《昆明医科大学学报》2014年第10期103-106,共4页Journal of Kunming Medical University

基　　金：安徽省卫生厅科学研究基金资助项目(09B128)

摘　　要：目的比较术前不同时间应用预防性抗生素治疗对输尿管镜下钬激光碎石的抗感染疗效的影响.方法回顾性分析自2008年1月至2013年8月就诊于安徽医科大学安庆附属医院行经尿道输尿管镜下钬激光碎石治疗治疗中、下段输尿管结石189例病例完整临床资料,排除术前发生泌尿道感染及失败患者11例,术前30min内应用抗生素头孢唑啉为A组,超过术前30 min应用抗生素头孢唑啉为B组.对2组患者的年龄、手术时间、结石大小、术后泌尿道感染发生率进行比较分析.结果 A组术后泌尿道感染发生率为16.05%,B组术后泌尿道感染发生率6.19%.2组患者的术后感染发生率比较差异有统计学意义(P<0.05).结论输尿管镜术前适当应用抗生素有利于控制泌尿道感染.Objective To evaluate the effect of the different opportunity for antibiotic prophylaxis in ureterscopic Holmium Laser Lithotripsy in the treatment of ureteral calculus.Methods We retrospectively analyzed the data of 178 patients treated with ureteroscopic holmium： YAG laser lithotripsy from January 2008 to January 2013 at the Department of Urology in Anqing municipal Hospital,including A group（81 cases preventative application of antibiotics before operation inside 30 minutes） and B group（97 cases preventative application of antibiotics before operation beyond 30 minutes）. We analyzed the variables such as patients infection,surgery time, and infection rate.Results The postoperation urinary infection rate in group A was 16.05%,while it was 6.19% in group B. The statistically significant difference was identified between the two groups in terms of the infection rate（P0.05）.Conclusion The earlier antibiotic prophylaxis of ureteral calculi with the ureteroscopic holmium laser lithotripsy will decrease the urinary infection rate.

关 键 词：抗生素 输尿管结石 输尿管镜 

分 类 号：R693.4[医药卫生—泌尿科学]