Epstein-Barr virus at 50——future perspectives  

作　　者：Lawrence S.Young 

机构地区：[1]Warwick Medical School,University of Warwick,Coventry,CV4 7AL,UK

出　　处：《Chinese Journal of Cancer》2014年第11期527-528,共2页

摘　　要：The special November and December issues of the Chinese Journal of Cancer celebrate the 50th anniversary of the discovery of Epstein-Barr virus(EBV) with a series of reviews covering the association of the virus with various cancers, with special emphasis on the role of EBV in the pathogenesis of nasopharyngeal cancer(NPC). The restricted geographic prevalence of NPC along with the tumor's consistent association with EBV infection has fascinated scientists and clinicians ever since it was first suggested in 1966. As in all cancers, NPC development reflects the complex interplay between host genes and environmental factors, but the essential role of EBV infection provides important insight into the etiology of this tumor. Indeed, it is this understanding that is now translating into exciting diagnostic and therapeutic opportunities.The special November and December issues of the Chinese Journal of Cancer celebrate the 50th anniversary of the discovery of Epstein-Barr virus（EBV） with a series of reviews covering the association of the virus with various cancers, with special emphasis on the role of EBV in the pathogenesis of nasopharyngeal cancer（NPC）. The restricted geographic prevalence of NPC along with the tumor＇s consistent association with EBV infection has fascinated scientists and clinicians ever since it was first suggested in 1966. As in all cancers, NPC development reflects the complex interplay between host genes and environmental factors, but the essential role of EBV infection provides important insight into the etiology of this tumor. Indeed, it is this understanding that is now translating into exciting diagnostic and therapeutic opportunities.

关 键 词：EPSTEIN-BARR病毒 病毒感染 NPC 发病机制 EB病毒 临床医生 相互作用 环境因素 

分 类 号：R373[医药卫生—病原生物学]