Entosis, a key player in cancer cell competition  被引量:2

Entosis, a key player in cancer cell competition

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作  者:Guido Kroemer 

机构地区:[1]Equipe 11 labellisee par la Ligue Nationale contre le Cancer, Centre de Recherche des Cordeliers, INSERM U1138, F-75006 Paris, France [2]Universite Paris Descartes, Sorbonne Paris Cite, F-75005 Paris, France [3]Metabolomics and Cell Biology Platforms, Gustave Roussy, F-94805 Villejuif, France [4]Pole de Biologie, Hopital Europeen Georges Pompidou, AP-HP, F-75015 Paris, France [5]Cell death and Aging team, Gustave Roussy, F-94805 Villejuif, France [6]Laboratory of Molecular Radiotherapy, INSERM U1030, Gustave Roussy, F-94805 Villejuif, France [7]Gustave Roussy, F-94805 Villejuif, France [8]Universite Paris Sud- Paris 11, F-94805 Villejuif, France

出  处:《Cell Research》2014年第11期1280-1281,共2页细胞研究(英文版)

摘  要:Cell-in-cell structures, also referred to as 'entosis', are frequently found in human malignancies, although their prognostic impact remains to be defined. Two articles recently published in Cell Research report the stimulation of entosis by one prominent oncogene, Kras, as well as by one class of tumor suppressors, namely epithelial cadherins E and P, illustrating the complex regulation of this biological process.

关 键 词:癌细胞 S期 竞争 球员 肿瘤抑制基因 细胞结构 恶性肿瘤 生物过程 

分 类 号:Q279[生物学—细胞生物学] S865.13[农业科学—野生动物驯养]

 

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