乌龟消化道的辐射损伤  

Radiation damage of alimentary tract of Chinemys reevesii

作　　者：李贵生[1] 刘加根[1] 

机构地区：[1]暨南大学生命科学技术学院生物工程学系,广东广州510632

出　　处：《暨南大学学报（自然科学与医学版）》2014年第6期507-512,524,共7页Journal of Jinan University(Natural Science & Medicine Edition)

基　　金：广东省科技计划项目(2012B020405006);广州市海洋与渔业自然保护区管理站项目(20080225)

摘　　要：对乌龟消化道的辐射损伤进行了研究.结果显示:乌龟消化道由5部分组成,即口咽腔、食道、胃、小肠和大肠.后4部分均由黏膜层、黏膜下层、肌层和外膜组成.消化道经X线辐射后的第1 d,食道黏膜层可见脱落和黏膜层细胞出现凋亡,黏膜下层血管出现栓塞和肌层血管出现凝血;胃、小肠和大肠的黏膜细胞及腺体细胞均出现凋亡.辐射后第8 d,食道黏膜层细胞凋亡加重,血管栓塞加重,外膜损伤明显,固有膜中的淋巴组织凋亡,腺体破坏严重;胃、小肠和大肠黏膜及腺体细胞凋亡加重,黏膜下层血管栓塞.辐射后第16 d,受损的食道黏膜层细胞和腺体结构修复,外膜恢复其完整性;胃、小肠和大肠黏膜细胞凋亡减少,新生细胞增多,血管栓塞减轻.The irradiation damage of aimentary tract of Chinemys reevesii was studied.The results showed that the aimentary tract of Chinemys reevesii were composed of five parts,including oropharyngeal cavity,esophagus,stomach,small intestine and large intestine.The behind four parts were composed of mucosa,submucosa,muscular layer and serosa.The first day after X-ray irradiation,some eophageal mu-cosa fell off,some mucosa cells were apoptosis,the submucosa blood vessels embolized and the myome-trial vessels had coagulation in esophagus.The mucosal cells and the glandular cells in stomach,small intestine and large intestine had apoptosis.The eighth day after irradiation,the apoptosis of the esophage-al mucosa and the embolism of blood vessel were more serious,the damage of serosa was obvious,the lymphatic tissue of proper coat had apoptosis,the damage of gland was serious in esophagus.The apopto-sis of the mucosal cells and the glandular cells were more serious and the submucosa blood vessels had embolism in stomach,small intestine and large intestine.The sixteenth day after irradiation,the damage esophageal mucosa and gland had repaired,the serosa restored the integrity in esophagus.The apoptosis of the mucosal cells reduced,the new cells increased and the vascular embolism alleviated in stomach, small intestine and large intestine.

关 键 词：乌龟 消化道 辐射损伤 

分 类 号：Q691.5[生物学—生物物理学]