低剂量多层螺旋CT引导下经皮肺穿刺活检的应用研究  

Application of low-dose multi-slice spiral CT-guided lung biopsy

作　　者：吴炅[1] 汪明全[1] 曾文兵[1] 高才良[1] 

机构地区：[1]重庆三峡中心医院放射科,重庆404000

出　　处：《放射学实践》2014年第11期1334-1337,共4页Radiologic Practice

基　　金：重庆万州区重点科技项目(201403006)

摘　　要：目的:探讨低剂量多层螺旋CT(MSCT)扫描技术在CT引导下经皮肺穿刺活检中应用的可行性及价值,降低患者辐射剂量。方法:回顾性分析50例采用常规剂量MSCT扫描技术(Thor Routine扫描序列:120kV,CARE Dose4D120mAs,螺距1.15,采集方式16×0.75mm)和50例采用低剂量扫描组合方案(Lung Low Dose扫描序列:80或120kV,CARE Dose 4D20mAs,螺距1.5,采集方式16×1.5mm;患者屏蔽防护)的CT引导下经皮肺穿刺活检,比较两组间图像质量、辐射剂量、穿刺活检诊断符合率以及并发症发生率。结果:低剂量组图像质量有所下降,但不影响穿刺活检的诊断符合率与安全性,两组间穿刺活检诊断符合率与并发症发生率差异均无统计学意义。常规剂量组与低剂量组的总毫安秒和总剂量长度乘积分别为(4476.06±1477.36)、(1027.18±296.19)mAs和(391.52±140.63)、(69.44±32.78)mGy·cm,且两组间差异均有统计学意义(P=0.000)。结论:低剂量MSCT扫描组合方案可以明显降低CT引导下经皮肺穿刺活检患者的辐射剂量,并且不会影响穿刺活检的诊断符合率和并发症发生率。Objective： To investigate the feasibility and application value of low-dose multislice spiral CT （MSCT） scanning technology in CT-guided percutaneous lung biopsy,in order to reduce the radiation dose for the patients. Methods： Retrospective analysis of 50 patients using conventional-dose MSCT scanning technology （Thor Routine scan sequence： 120 kV,CARE Dose 4D 120mAs,pitch of 1. 15,acquisition method 16×0.75mm） and the other 50 cases using low dose scanning combined plan （Lung Low Dose scan sequence：80 or 120kV,CARE Dose 4D 20mAs, pitch of 1.5, acquisition method 16 ×1.5mm, shielding protection） in CT-guided percutaneous lung biopsy. Image quality and radiation dose, coincidence rate of biopsy and the incidence of complications between two groups were compared. Results： In the low dose group, image quali- ty declined,but it did not affect the accuracy and safety of biopsy. The differences of coincidence rate of biopsy and incidence of complications between the two groups were not statistically significant. Total mAs and Total DLP of regular dose group and low dose group were （4476. 06±11477.36） ,（1027.18±296. 19）mAs and （391.52± 140.63）, （69.44±32.78）mGy. cm,respctively,and the differences of which were statistically significant between the two groups （P= 0. 000）. Conclusion： Combined scheme of low-dose multislice CT scan can significantly reduce the radiation dose of CT-guided lung biopsy and does not affect the coincidence rate of biopsy and the incidence of complications.

关 键 词：体层摄影术 X线计算机 低剂量扫描 CT引导 活组织检查 辐射剂量 

分 类 号：R816.4[医药卫生—放射医学]