广西沿海、平原、山区8～10岁儿童碘营养状况分析  

Analysis of urinary iodine level of 8-10 years old children in coastal, plain and mountain areas in Guangxi

作　　者：吕群[1] 耿国兴[1] 陈少科[1] 林飞[1] 罗超[1] 覃旺尚 徐钰琪 韦荣敏[1] 何春雨[1] 

机构地区：[1]广西壮族自治区妇幼保健院遗传代谢中心实验室,南宁530000

出　　处：《中华地方病学杂志》2014年第6期657-659,共3页Chinese Journal of Endemiology

基　　金：国家自然科学基金（81260126）;广西自然科学基金（2012GXNXFAA053174）：广西卫生厅重点课题（重2012025）

摘　　要：目的 了解广西沿海、平原、山区8～ 10岁儿童碘营养状况.方法 按照分层整群抽样方法,在广西新生儿疾病筛查中心管辖内直接筛查先天性甲状腺功能减低症的协作市、县（区）,抽取2个沿海县（区）、3个平原县（区）、4个山区县（区）,每个县（区）按人口情况抽取8～ 10岁儿童作为观察对象.采集儿童中段尿,采用砷铈催化分光光度法检测尿碘水平.结果 共测定2 073名8～ 10岁儿童尿样,尿碘中位数为175.31μg/L,范围为20.57 ～ 929.30 μg/L,其中＜100 μg/L的比例为20.31％（421/2 073）,100 ～ 199 μg/L的比例为40.38％（837/2 073）,200～ 299 μg/L的比例为27.54％（571/2073）,≥300 μg/L的比例为11.77％ （244/2073）.男性、女性儿童尿碘中位数分别为183.79、161.11 μg/L,＜100 μg/L的比例分别为17.40％（194/1115）、23.70％（227/958）,二者比较差异有统计学意义（x2=12.621,P＜0.01）;8、9、10岁组儿童尿碘中位数分别为164.75、167.56、179.52 μg/L,＜100 μg/L的比例分别为19.94％（128/642）、21.36％ （233/1 091）、17.65％（60/340）,组间比较差异无统计学意义（P＞0.05）;沿海、平原、山区儿童尿碘中位数分别为151.23、169.17、190.36 μg/L,＜100μg/L的比例分别为26.44％（147/556）、22.67％（175/772）、12.08％（90/745）,沿海、平原儿童与山区儿童比较差异均有统计学意义（x2值分别为44.058、29.479,P均＜0.01）.结论 广西沿海、平原、山区8～ 10岁儿童碘营养状况处于适宜水平（国家标准：尿碘100～ 199 μg/L为碘适宜）,但尿碘中位数呈现沿海＜平原＜山区态势,应当引起政府有关部门和碘缺乏病防治工作者的重视.Objective To investigate the iodine nutritional status of children aged 8-10 in coastl,plain and mountain areas of Guangxi.Methods According to stratified cluster sampling method,collaborative cities and counties （districts） with Guangxi Center for Newborn Disease Screening,including two coastal counties （districts）,three plain counties（districts） and four mountain counties（districts）,were selected.Midstream urine of 8-10 years old children was collected,and arsenic cerium catalytic spectrophotometry was used to measure urinary iodine level.Results Totally 2 073 urine samples were measured in 8-10 years old children,and iodine levels were 20.57-929.30 μg/L; the median was 175.32 μg/L; 〈 100 μg/L was 20.31%（421/2 073） ; 100-199 μg/L was 40.38% （837/2 073）; 200-299 μg/L was 27.54% （571/2 073）; and ≥300 μg/L was 11.77% （244/2 073）.Among them,boys median was 183.79 μg/L; girls median was 161.11 μg/L; less than 100 μg/L were 17.40%（194/ 1 115） and 23.70% （227/958）,respectively,the difference was statistically significant （x2 =12.621,P 〈 0.01）.The median of urinary iodine in 8,9 and 10 years old children was 164.75,167.56,179.25 μg/L,respectively; less than 100 μg/L were 19.94% （128/642）,21.36% （233/1 091） and 17.65% （60/340）,respectively,the differences were not statistically significant （P 〉 0.05）.The median of urinary iodine in 8-10 years old children in coastal,plain and mountain areas was 151.23,169.17,190.36 μg/L,respectively; less than 100 μg/L were 26.44% （147/556）,22.67% （175/772） and 12.08% （90/745）,respectively,the differences were statistically significant between coastal,plain and mountain areas （x2 =44.058,29.479,all P 〈 0.01）.Conclusions Iodine nutrition of most 8-10 years old children in Guangxi coastal,plain and mountain areas is at an appropriate level （national standards：median of urinary iodine is 100-199 μg/L）.However,the median of urinary iodine has presented in the order of coastal 〈 plain

关 键 词：碘 营养调查 儿童 尿 

分 类 号：R599[医药卫生—内科学]