Monitor In Vivo Dynamics of Avian Influenza Viruses Using Bioorthogonal-conjugated Nearinfrared Quantum Dots  

出　　处：《Bulletin of the Chinese Academy of Sciences》2014年第4期331-332,共2页中国科学院院刊（英文版）

基　　金：supported by the National Basic Research Program of China;the National Natural Science Foundation of China;the‘‘Hundred Talents Program’’of the Chinese Academy of Sciences;the Science and Technology Foundation of Guangdong Province;Guangdong Innovation Research Team of Low-cost Healthcare;the SIAT Innovation Program for Excellent Young Researchers

摘　　要：Highly pathogenic avian influenza A viruses are emerging pandemic threats that have caused several outbreaks with high mortality in human beings in the past decades.The infection of avian infl uenza viruses,such as subtype H5 and H7,could cause a series of severe respiratory and extra-respiratory complications,Highly pathogenic avian influenza A viruses are emerging pandemic threats that have caused .several outbreaks with high mortality in human beings in the past decades. The infection of avian influenza viruses, such as subtype H5 and H7, could cause a series of severe respiratory and extra-respiratory complications, both of which are directly associated with viral loading and dissemination in tissues. Understanding the route and pathogenesis of avian influenza viral infection is extremely important for developing prophylactic and therapeutic strategies against viral infections. Although the studies using cell cultures have made significant contributions to exploring the pathogenesis of avian influenza viruses, it is highly desirable to track the in vivo dynamics of viral infection in order to further dissect the interactions between the virus and the host.

关 键 词：高致病性禽流感 体内动力学 量子点 近红外 禽流感病毒 监测 正交 生物 

分 类 号：S852.65[农业科学—基础兽医学]