2012-2013年包头市过敏性哮喘群体过敏原检测  

Detection of the Allergen for Allergic Asthma Individuals in 2012-2013 in Baotou

作　　者：高扬[1] 唐存亮[1] 姚洁 李冬梅[1] 杨月元[1] 张毅[1] 李水霞[1] 马显军[1] 孙丽蓉[1] 

机构地区：[1]包头医学院第二附属医院,内蒙古包头014030 [2]包钢三医院心理康复科

出　　处：《包头医学院学报》2014年第5期15-16,19,共3页Journal of Baotou Medical College

摘　　要：目的:研究集中爆发期间患者血清特异性Ig E过敏原种类及其与非集中发作期病例过敏原间的差别。方法:对爆发发病期间的78例过敏性哮喘患者及同期74例非集中发作期患者,检查血清中的Ig E型变应原抗体来确定过敏原,对比两类病例过敏原是否存在差别。结果:集中发作期患者血清特异性Ig E检测中,阳性率最高的前3位变应原分别是蒿/矮豚草67例(85.9%)、苋/藜/葎草/蒲公英62例(79.4%)、柏/榆/梧/柳/杨/榛48例(61.5%);集中发作期患者苋/藜/葎草/蒲公英(10.76±26.97)IU/m L,蒿/矮豚草(27.62±40.81)IU/m L,柏/榆/梧/柳/杨/榛(0.44±1.253)IU/m L,与非集中发作期患者比较差异有统计学意义(P<0.05)。结论:集中发作期患者与非集中发作期患者的过敏原种类存在差别。Objective：To investigate the difference between the types of specific serum IgE allergen in allergic asthma pa-tients during the concentrated attack and the allergen of allergic asthma patients during non - concentrated attack. Methods：The anti - IgE allergen antibody in the serum was detected in 78 cases of allergic asthma during concentrated attack and in 74 ca-ses of allergic asthma during non - concentrated attack to decide the allergen,with a comparison made in the allergen between the two groups of allergic asthma patients. Results：The first three highest specific serum IgE allergen positive rates in those dur-ing concentrated attack were Artemisia/ short ragweed（67 cases,85. 9 % ）,amaranth/ quinoa/ humulus/ Dandelion（62 cases, 79. 4 % ）and Bai Yu Wu Liuyang hazel（48 cases,61. 5 % ）. Amaranth/ quinoa/ humulus/ Dandelion,Artemisia/ short ragweed and Bo Yu Wu Liuyang haze were 10. 76 ± 26. 97 IU/ mL,27. 62 ± 40. 81 IU/ mL and 0. 44 ± 1. 253 IU/ mL,respectively,in the patients during concentrated attack,with significant difference from those in the patients during non - concentrated attack（ P 〈0. 05）. Conclusion：There is a difference in the allergen type between the concentrated attack patients and non - concentrated attack ones.

关 键 词：过敏原 特异性Ig E 群体发病 哮喘 

分 类 号：R562.25[医药卫生—呼吸系统] R446.6[医药卫生—内科学]