正常人群血浆脂肪源性因子水平与体质量的相关性  

Correlation between plasma apelin levels and body mass in normal population

作　　者：施京君 邓婷[1] 马旭华[1] 朱佳隽[1] 曹英川 张红亚[1] 

机构地区：[1]上海市杨浦区疾病预防控制中心,中国上海200090

出　　处：《临床心身疾病杂志》2014年第6期1-2,共2页Journal of Clinical Psychosomatic Diseases

基　　金：上海市卫生和计划生育委员会科研计划资助项目（编号201440285）

摘　　要：目的 探讨正常人群血浆脂肪源性因子水平与体质量的相关性.方法 将80名健康志愿者根据2012年世界卫生组织制定的肥胖诊断标准分为超重/肥胖组（41名）和正常体质量组（39名）,分别检测空腹血浆脂肪源性因子、血压水平及体质量指数.结果 超重/肥胖组血浆脂肪源性因子水平、收缩压、舒张压及体质量指数均显著高于正常体质量组（P＜0.01）.偏相关分析显示,血浆脂肪源性因子与体质量指数呈正相关（r=0.253,P＜0.05）.结论 体质量指数增高可能是引起血清脂肪源性因子水平升高的主要因素.Objective To explore the correlation between plasma apelin levels and body mass （BM） in normal population. Methods Eighty healthy volunteers were divided into overweight/obesity （n = 41） and normal BM group （n=39） according to the WHO Diagnostic Criteria for Obesity in 2012, fasting plasma apelin, blood presure and body mass index （BMI） detected. Results Plasma apelin levels, systolic and diastolic blood pressure as well as BMI were all significantly higher in overweight/obesity than normal BM group（P〈0. 01）. Partial correlation analysis showed that plasma apelin was positively correlated with BMI （r=0. 253,P〈0.05）. Conclusion BMI increase could be a main factor causing serum apelin level elevation.

关 键 词：脂肪细胞因子 脂肪源性因子 空腹血浆 超重/肥胖 体质量 体质量指数 

分 类 号：R589.2[医药卫生—内分泌]