水合氯醛不同给药途径下儿童镇静效果比较的Meta分析  

Sedation with oral or rectal chloral hydrate in pediatric patients：A Meta-analysis

作　　者：丁国建[1] 刘希杰[1] 徐传臻[1] 耿磊[1] 傅廷亮[1] 

机构地区：[1]滨州医学院附属医院儿外科,256603

出　　处：《中国实用护理杂志》2014年第31期55-58,共4页Chinese Journal of Practical Nursing

摘　　要：目的 用Meta分析的方法比较水合氯醛口服和直肠内给药的镇静效果.方法 收集比较水合氯醛口服和直肠内给药镇静效果的随机对照研究,采用RevMan5.0软件对纳入的10篇文献进行统计学分析.结果 经分析直肠内给药有效率高于口服给药.口服给药患儿有95例出现胃肠道反应,直肠内给药有57例出现排便反应.结论 水合氯醛直肠内给药的镇静效果优于口服给药.儿科应用水合氯醛镇静时特别注意用药安全,避免药物不良反应发生.Objective To compare the sedative efficacy with oral or rectal chloral hydrate in pediatric patients by using Meta-analysis method.Methods Ten randomized controlled trials about the sedative efficacy with oral or rectal chloral hydrate in pediatric patients were retrieved.Meta-analysis was carried out using the RevMan 5.0 software.Results The results showed that the sedative efficacy with rectal medication was better than that with oral way.Nausea and vomiting occurred in 95 children with oral chloral hydrate,bowel movement occurred in 57 children with rectal chloral hydrate.Conclusions The sedative efficacy with rectal chloral hydrate was better than that with oral way.The safety in pediatric sedation with chloral hydrate should be emphasized in order to avoid adverse reaction.

关 键 词：水合氯醛 镇静 儿童 

分 类 号：R473.72[医药卫生—护理学]