老年急性肾衰竭412例预后影响因素分析  

Influencing Factors of the Prognosis in 412 Elderly Patients with Acute Renal Failure

作　　者：李庆华[1] 陈静[1] 谭清武[1] 唐静怡[1] 

机构地区：[1]解放军白求恩国际和平医院干部病房,石家庄050082

出　　处：《解放军医药杂志》2014年第11期75-78,共4页Medical & Pharmaceutical Journal of Chinese People’s Liberation Army

摘　　要：目的探讨影响老年急性肾衰竭(ARF)患者预后的因素。方法对解放军白求恩国际和平医院干部病房2005年1月—2013年1月住院的412例老年ARF的临床资料进行回顾性分析。结果 412例ARF中,感染、心力衰竭、肾毒性药物、肿瘤、手术为导致老年ARF的常见原因(分别占38.4%、21.6%、18.0%、9.0%、6.1%)。单因素分析提示,感染、应用肾毒性药物、心力衰竭、高龄(≥80岁)、合并多器官功能不全综合征(MODS)、有慢性肾脏病史与老年ARF患者的预后密切相关(P<0.01,P<0.05)。logistic回归分析显示,感染、应用肾毒性药物、心力衰竭、高龄(≥80岁)、合并多器官功能障碍综合征(MODS)是影响老年ARF患者预后的独立危险因素(P<0.05)。结论应充分重视影响老年ARF预后的相关因素,及时给予针对性治疗,以降低病死率、改善预后。Objective To investigate the influencing factors of the prognosis in elderly patients with acute renal failure（ ARF）. Methods Clinical data of 412 elderly patients with ARF during January 2005 and January 2013 was retrospectively analyzed. Results The common causes of induced ARF in the 412 elderly patients were infection,heart failure,application of renal toxicity drugs,tumor and surgery,and the corresponding rates were 38. 4%,21. 6%,18. 0%,9. 0% and 6. 1% respectively. The single factor analysis showed that infection,application of renal toxicity drugs,heart failure,aged（ ≥80 years old）,complication of MODS（ multiple organ dysfunction syndrome） and history of chronic renal disease were closely related with prognosis（ P〈0. 01,P 〈0. 05）. The Logistic Regression Analysis showed that infection,application of renal toxicity drugs,heart failure,aged（ ≥80 years old） and complication of MODS were independent risk factors of the prognosis in elderly patients with ARF（ P 〈0. 05）. Conclusion Influencing factors of prognosis should be given more attention in elderly patients with ARF,and pertinent treatment should be taken to reduce mortality rate and improve prognosis.

关 键 词：肾功能不全 急性 老年人 预后 影响因素分析 

分 类 号：R692.5[医药卫生—泌尿科学]