江苏10家医院供应的五味子中木脂素类成分含量测定比较  

Comparison of Lignanoids in Schisandra chinensis from 10 Hospitals of Jiangsu Province

作　　者：黄国兴[1] 安莉萍[2] 窦志华[3] 张琳[3] 施凯[3] 

机构地区：[1]苏州永鼎医院,江苏苏州215200 [2]南京中医药大学,江苏南京210023 [3]南通大学附属南通第三医院,江苏南通226006

出　　处：《中医药导报》2014年第15期27-29,共3页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：江苏省药学会科研项目(JS2012-04);江苏省南通市应用研究计划项目(K2008027)

摘　　要：目的:对10家医院供应的五味子进行质量评价。方法:采用高效液相色谱及已建立的一测多评法,以五味子醇甲为内参物,测定五味子醇甲、五味子醇乙、五味子酯甲、五味子甲素、五味子乙素及五味子丙素的含量,分光光度法测定总木脂素含量。结果:10家医院供应的五味子中五味子醇甲、五味子醇乙、五味子酯甲、五味子甲素、五味子乙素、五味子丙素和总木脂素含量分别在3.935-6.809、1.389-2.583、0.191-0.436、0.961-1.767、2.030-3.716、0.261-0.813及19.696-34.294mg/g之间;结论:各医院供应的五味子内在质量有较大差异。Objective： To evaluate the quality of Wuweizi（Schisandra chinensis） from 10 hospitals of Jiangsu province.Methods：Content of schizandrol A, schizandrol B, schisantherin A, deoxyschizandrin, schizandrin B, and schizandrin C were de-termined by HPLC and established multi-components by single marker（QAMS） method selecting schizandrol A as internal refer-ence. Total lignanoid was determined by spectrophotometric method. Results ： The content of schizandrol A, schizandrol B,schisantherin A, deoxyschizandrin, schizandrin B, schizandrin C and total lignanoid were between 3.935-6.809, 1.389-2.583, 0.191-0.436, 0.961-1.767, 2.030-3.716, 0.261-0.813 and 19.696-34.294 mg/g, respectively. Conclusion：There is a comparatively large difference in internal quality of S. chinensis from different hospital.

关 键 词：五味子 木脂素 含量测定 高效液相色谱法 一测多评 分光光度法 

分 类 号：R284.1[医药卫生—中药学]