老年血脂异常的防治  

Prevention and treatment of in the elderly

作　　者：王川[1] 严励[1] 

机构地区：[1]中山大学附属孙逸仙纪念医院内分泌科,广州510120

出　　处：《中华内分泌代谢杂志》2014年第11期1035-1038,共4页Chinese Journal of Endocrinology and Metabolism

摘　　要：老年血脂异常危害严重,但对该病的防治还不尽人意,临床实践与指南仍有较大差距.降低低密度脂蛋白胆固醇是老年血脂异常防治的首要目标.生活方式调整和他汀类仍是老年血脂异常治疗的基石,但在大剂量使用他汀类时应注意其不良反应,如肌酶的升高以及发生糖尿病风险的增加等.他汀类联合其他调脂药能否降低残留心血管风险,仍需进一步研究证实.Dyslipidemia is one of the major risk factors for cardiovascular disease in elderly,but clinical practices in the management of elderly dyslipidemia are still not satisfactory.The cornerstone of treatment for elderly dyslipidemia consists of therapeutic lifestyle change and statins.Recent guidelines emphasize aggressive low density lipoprotein-cholesterol control with statins.However,intensive statin therapy may increase the risk of myopathy and diabetes.Therefore,it is important to consider risk benefit ratio in individual patients.The additional benefit of statins in combination with other hypolipidemic drugs on cardiovascular risk still needs verifying by further investigation.

关 键 词：老年 心血管疾病 血脂异常 

分 类 号：R589.2[医药卫生—内分泌]