FLAIR序列参数优化对图像质量的研究  

Study of optimization of FLAIR pulse sequence for image quality

作　　者：孙伟[1] 姚秀忠[1] 冯豪[1] 张澍杰[1] 陈财忠[1] 曾蒙苏[1] 

机构地区：[1]复旦大学附属中山医院放射诊断科,复旦大学上海医学院影像学系,上海市影像医学研究所,上海200032

出　　处：《实用放射学杂志》2014年第11期1906-1909,1954,共5页Journal of Practical Radiology

摘　　要：目的探讨磁共振头颅轴位液体衰减反转恢复（FLAIR）序列临床应用中，改变扫描参数及使用不同扫描技术对图像质量和成像时间的影响。方法对30例患者行7种不同参数的T2-FLAIR扫描：A组为常规检查序列，为参考组；B组减少成像矩阵至128；C组增加加速因子（Turto factor）至24；D组图像采集组数（contatenation）参数设为1；E组并行采集因子（Accel．factor PE）参数设为4；F组采用刀锋序列（BLADE）技术；G组采用半傅里叶扫描（HASTE）技术。对所得各组图像测量信噪比并让3位磁共振专家对所得图像质量进行独立观察及评分，图像信噪比采用单因素方差分析，图像质量评分采用Kruskal-Wallis非参数检验。结果7组图像信噪比分别为54．69±8．12，157．57±25．61，44．56±7．37，38．48±9．32，44．19±8．79，45．60土6．92，105．20±18．25，差异有统计学意义（F=266．368，P=0．000）。7组图像质量评分分别为3．87±0.09，2．50±0．12，3．72土0．16，3．10±0．10，1．88±0．10，3．92±0．07，2．08±0．10，差异有统计学意义（χ^2=193．361，P=0．000）。结论合适的Turto factor及BLADE可以获得有价值的图像。HASTE技术可以作为补充序列。Objective To explore the effect on image quality and scanning time by changing parameters and using different scanning technique for the clinical application of axial FLAIR pulse sequence. Methods Seven different sets of parameters of T2-FLAIR Pulse Sequences were performed on thirty patients at a 3.0 T MR scanner. Group A was scanned with a routine sequence for reference. Group B, reducing the matrix to 128. Group C, increasing the turbo factor parameter to 24. Group D, setting the contatenation to 1. Group E setting the Accel. factor PE to 4. Group F, using a BLADE-FLAIR sequence. Group G, using a HASTE-FLAIR sequence. The SNRs of all images were statistically analyzed by ANOV A among 7 sequences. The image quality of all images was statistically analyzed by Kruskal-Wallis test among 7 sequences. Results The SNR of seven groups of images were 54. 69±8. 12, 157. 57 ± 25. 61,44.56 ± 7. 37,38. 48 ± 9. 32,44. 19 ± 8. 79,45. 60 ± 6. 92,105. 20 ± 18. 25, respectively （F = 266. 368, P = 0. 000）. The scores of image quality were 3. 87±0. 09,2. 50±0. 12,3. 72±0.16, 3. 10±0. 10, 1. 88±0.10, 3. 92±0. 07,2. 08±0. 10,respectively and the differences among groups were statistically significant（χ^2 = 193.361, P= 0.000）. Conclusion Suitable turto factor and BLADE technique can be the best option for FLAIR sequence in the head. HASTE-FLAIR sequence can act as the secondary option for the uncooperative patients.

关 键 词：磁共振成像 液体衰减反转恢复序列 脑 

分 类 号：R445.2[医药卫生—影像医学与核医学] R322.81[医药卫生—诊断学]