自体富血小板血浆凝胶治疗电烧伤残余创面的疗效观察  

Curative effect of autologous platelet rich plasma gel in the treatment of electrical burn residual wound

作　　者：吴宏志[1] 杨蒙[1] 魏伟[1] 李晓[2] 冯建科[1] 白永强[1] 张庆富[1] 

机构地区：[1]河北医科大学第一医院烧伤整形科,河北石家庄050031 [2]石家庄市第一医院消化内科,河北石家庄050000

出　　处：《海南医学院学报》2015年第1期96-98,共3页Journal of Hainan Medical University

基　　金：河北省卫生厅医学科学研究重点课题计划(20130261)~~

摘　　要：目的:探讨自体富血小板血浆凝胶治疗电烧伤残余创面的临床疗效。方法:在我院就诊的72例电烧伤患者,随机分为两组,各36例。观察组根据电烧伤创面深度分为A、B组,A组给予富血小板血浆外敷,B组注射富血小板血浆。对照组按烧伤创面情况分为a、b组,a组覆盖生物皮治疗,b组行断层皮片移植治疗。结果:观察组患者愈合率(83.33%)高于对照组(55.56%),差异具有统计学意义(P<0.05)。A、B组愈合时间少于a、b组愈合时间,差异具有统计学意义(P<0.05)。治疗后2周,观察组患者创面疼痛评分、瘢痕评分明显低于对照组患者瘢痕评分,差异具有统计学意义(P<0.01)。治疗后1、2周,观察组患者血液灌流值高于对照组值,差异均具有统计学意义(P<0.01)。观察组患者不良反应发生率低于对照组,差异具有统计学意义(P<0.05)。结论:自体富血小板血浆凝胶治疗电烧伤残余创面临床疗效显著,能够有效缩短愈合时间,减轻患者疼痛,改善微循环。Objective：To observe the curative effect of autologous platelet rich plasma gel in the treatment of electrical burn residual wound.Methods：A total of 72 cases of electric burn were randomly divided into two groups by half.According to the deep electric burn wounds patients were divided into A group,B group.Patients in A group had external application of platelet rich plasma,while patients in Group B had injection of platelet rich plasma.Patients in control group with the burn wound were divided into two groups.Patients in Group had covering biological skin treatment,and patients in Group b had fault skin grafting.Results：The healing rate of the observation group was significantly higher than that of control group（P 〈0.05）.The healing time in observation groups were significantly shorter than those in control groups（P 〈 0.05）.After 2weeks of treatment,wound pain score and scar score in the observation group was lower than control groups,with significant difference（P 〈 0.01）.After treatment for 1week,2weeks,blood flow changes in the observation groups were significantly higher than control groups（P 〈 0.01）.The incidence of adverse reactions in the observation groups was significantly lower than control groups（P 〈 0.05）.Conclusion：Autologous platelet rich plasma gel has good clinical effect in the treatment of electrical burn residual wound.It can effectively shorten the healing time,reduce the pain of patients,and improve microcirculation.

关 键 词：自体富血小板血浆凝胶 电烧伤 残余创面 生长因子 

分 类 号：R644[医药卫生—外科学]