400份学龄儿童尿碘浓度监测分析和方法验证  

Monitoring analysis and validation of the method of urine iodine level in 400 children 8-10 years old

作　　者：耿国兴[1] 吕群[1] 覃旺尚 徐钰琪 陈少科[1] 

机构地区：[1]广西壮族自治区妇幼保健院遗传代谢中心实验室,广西南宁530003

出　　处：《现代预防医学》2015年第1期49-50,75,共3页Modern Preventive Medicine

基　　金：国家自然科学基金(81260126)

摘　　要：目的了解市区和县区碘营养状况，并对改进后的方法进行验证。方法随机抽取400名8～10岁学龄儿童进行尿碘测定，尿碘检测采用砷铈催化分光光度法。结果改进后方法的检出限为7．12μg／L，相对标准偏差介于1．61％-3．44％，不同浓度尿样的平均加标回收率介于98．25％～102．45％，市区和县区的尿碘中位数相近。结论改进后的方法线性，准确度和精密度符合要求，被监测地区儿童碘营养状况良好。Objective To investigate iodine nutrition status of children 8-10 years in cities and counties and to validate the improved method. Methods A total of 400 children 8-10 years old were randomly selected from those districts. The urinary iodine was measured by Ce arsenic acid digestion. Results The limit of detection is 7.12μg/L, and the relative standard deviation is in the range of 1.61%-3.44%. The method has been applied to the determination of iodine in urine samples, and the recoveries are in the range of 98.25%-102.45%. Conclusion The linearity, precision and accurancy were consistent with the experimental standard. The iodine nutrition status of school children was basically adequate in those areas.

关 键 词：尿碘 对比分析 方法验证 

分 类 号：R179[医药卫生—妇幼卫生保健]