参麦注射液对慢性阻塞性肺病急性加重期患者炎性标志物的影响  

Effects of Shenmai injection on inflammatory markers of patients with acutechronic obstructive pulmonary disease

作　　者：张春云[1] 何耀军[1] 林纯意[1] 

机构地区：[1]广州医科大学附属第五医院呼吸内科,广东广州510700

出　　处：《广州医学院学报》2014年第3期58-59,66,共3页Academic Journal of Guangzhou Medical College

摘　　要：目的:观察参麦注射液对慢性阻塞性肺疾病急性加重期(AECOPD)患者外周血白细胞、C反应蛋白(CRP)、前降钙素原(PCT)的影响。方法:将2012年8月至2013年8月本科收治的68例AECOPD患者作为研究对象,其中治疗组34例、对照组34例。对照组采用平喘、吸氧、雾化吸入、呼吸功能锻炼,抗感染治疗等:治疗组在此基础上加用参麦注射液,疗程为7 d。入院1 d和治疗7 d时测定外周血白细胞、CRP、PCT。结果:两组治疗后外周血白细胞、PCT、CRP水平均较治疗前降低(P<0.05),但治疗组治疗后上述指标较对照组降低更加明显(P<0.05)。结论:参麦注射液能显著降低AECOPD患者的炎症反应,是辅助治疗的理想药物之一。Objective： To investigate the effects of Shenmai injection in peripheral blood leucocyte、 C-reactive protein （ CRP） 、 Procalcitonin （ PCT） of patients with acute-chronic obstructive pulmonary disease. Methods： Sixty-eight patients with acute-chronic obstructive pulmonary disease were divided into therapy group （34 cases） and control group（34 cases） . Tow groups were treated by Western medicine,the therapy group were treated by the Shenmai injection at the same time ,Seven days for a course. The peripheral blood leucocyte and CRP and PCT levels were detected in all patients at the first day and the seventh day. Results： The level of the peripheral blood leucocyte and CRP and PCT in therapy group were remarkably reduced after training （P〈0.05-0.01） and were lowed than those in control group after training （P〈0.05）. Conclusions：The Shenmai injection can remarkably cut down the infected reaction of patients with acute-chronic obstructive pulmonary disease,it is one of the better auxiliary drug to tread chronic obstructive pulmonary disease.

关 键 词：慢性阻塞性肺病 急性加重期 参麦注射液 炎性标志物 

分 类 号：R473.5[医药卫生—护理学]