新生儿皮下脂肪坏死1例报告及文献回顾  

Subcutaneous fat necrosis in neonate: a case report and literature review

作　　者：王贝贝[1] 周晓光[1] 周晓玉[1] 

机构地区：[1]南京医科大学附属南京儿童医院,江苏南京210008

出　　处：《临床儿科杂志》2014年第11期1048-1051,共4页Journal of Clinical Pediatrics

摘　　要：目的探讨新生儿皮下脂肪坏死(Sc FN)的诊断与治疗。方法回顾性分析1例Sc FN患儿的临床资料,并结合文献分析Sc FN的病因、发病机制、鉴别诊断等。结果女性患儿,足月剖宫产,生后2 d因背部、肩部皮下硬结半天入院,抗感染治疗不佳。入院第10天患儿背部硬结局部出现软化、波动,局部穿刺液镜检示少量炎症细胞浸润,脂肪细胞变性,诊断为Sc FN。随访2月肿块消退,全身状况良好。结论 Sc FN是一种良性脂肪疾病,大多发生在有异常分娩史的足月新生儿,常发生于生后4周内,为自限性疾患,预后良好。Objective To investigate diagnostic methods and treatment of subcutaneous fat necrosis in neonate （ScFN）. Methods The clinical data of a case with ScFN was reported and the etiology, pathogenesis, and differential diagnosis were reviewed. Results The case was a 2 days female newborn delivered via cesarean section at full-term, and she came to hospital because of indurated nodules and plaques in the back and shoulders. Anti-infection treatment after admission was not effective. On the 10th day in hospital, the back lesions appear as soft and lfuctuant and then diagnosed as ScFN by biopsy which showed a small amount of inflammatory cell infiltration and fatty degeneration. The patient was followed up with good prognosis. Conclusions ScFN is a benign self-limiting fat disease, mostly occurred in the first four weeks of full-term newborns with history of abnormal childbirth.

关 键 词：皮下脂肪坏死 诊断 新生儿 

分 类 号：R722.1[医药卫生—儿科]