碱水提取复方灵丹胶囊中灵芝多糖的工艺  

Study on Optimum Extracting Conditions of Total Polysaccharides from Ganoderma lucidum of Lingdan Capsule by Alkaline Solutions

作　　者：叶豆丹[1] 孟美[1] 王化宇[1] 任钰[1] 张炜煜[1] 

机构地区：[1]长春中医药大学,吉林长春130117

出　　处：《食品研究与开发》2014年第17期36-38,共3页Food Research and Development

基　　金：院内制剂"复方灵丹胶囊"制备工艺研究;吉林省科技厅;2011年;项目任务书编号:20110949

摘　　要：试验优选了碱水提取法提取复方灵丹胶囊中灵芝多糖的最佳工艺。以总多糖的含量为考察指标,采用单因素法和正交试验法确定方中灵芝多糖最佳提取工艺。结果最佳提取工艺为加10倍于药材量的水(pH=9)煎煮2次,每次1.0 h。该提取工艺操作简单、稳定可行,适合于产业化生产,并具有良好的应用前景。To optimize the extraction technology of effective fraction of Ganoderma lucidum. To regard the contents of total polysaccharides as the examinational indicators, to decide the extraction methods by L9 （34） orthogonal test and single factor method for total polysaccharides components of Ganoderma lucidum. The optimal extraction of total polysaccharides in Ganoderma lucidum is medicinal materials plus 10 times the amount of water （pH=9）, extract twice and 1.0 h per time. The optimum extraction technology of total polysaccharides from Ganoderma lucidum is simple, stable and feasible, suitable for industrial production, and has a good prospect.

关 键 词：灵芝 总多糖 提取工艺 正交试验 

分 类 号：R286.0[医药卫生—中药学] TQ461[医药卫生—中医学]