L-(+)-酒石酸酯类化合物的合成研究  

Study on the Synthesis of L-(+)-Tartaric Acid Ester Compounds

作　　者：计海峰[1] 刘保雷[1] 刘放[1] 王卫东[1] 

机构地区：[1]吉林化工学院,吉林吉林132022

出　　处：《广州化工》2014年第22期95-96,130,共3页GuangZhou Chemical Industry

摘　　要：以L-(+)-酒石酸为原料,在酸醇摩尔比为1∶2.8,甲苯为溶剂的条件下,合成L-(+)-酒石酸二卞酯,分析产物的旋光性,其结构经1H-NMR和IR表征。分别以硼酸、浓硫酸、对甲苯磺酸以及732型强酸性阳离子树脂作为催化剂,考察催化效果。实验结果表明,以硼酸作为催化剂,产物的比旋光度为+5.325,收率达到83.57%,且能多次回收利用;硼酸用于催化手性酒石酸酯类化合物效果明显,选择性好,得到的酯收率较高。With tartaric acid as raw material for synthesis of dibezyl L-tartrate, the reaction factors were determined by the molar ratio of acid to alcohol of 1：2. 8 and toluene as solvent. The structure of the product was confirmed by 1 H-NMR and IR and specific rotation analysis. The catalytic effects of boric acid, sulfuric acid, p-toluenesulfonic acid and 732 strong acid cation resin as a catalyst were studied, the experimental results showed that the product of specific rotation was ＋5. 325 , 83. 57% of the receiving rate reached and boric acid as catalyst can be reused many times. The catalytic effects of chiral tartrate compounds obviously, good selectivity, and high yield of the ester obtained.

关 键 词：L-(+)-酒石酸 硼酸 手性 

分 类 号：O632.62[理学—高分子化学]