新型气相毛细管柱的制备及对苯系位置异构体的色谱分离  

Preparation of New Gas Phase Capillary Columns Coated with β-Cyclodextrin Derivatives and Separation Behaviors toward Benzene Positional Isomers

作　　者：贾成俊[1] 颜霞[1] 范军[1] 郑盛润[1] 章伟光[1] 

机构地区：[1]华南师范大学化学与环境学院,广州510006

出　　处：《华南师范大学学报（自然科学版）》2014年第6期80-84,共5页Journal of South China Normal University(Natural Science Edition)

基　　金：国家自然科学基金项目(21171059);广州市科技计划项目(2011Y3-00040)

摘　　要：将羟丙基-β-环糊精(HP-β-CD)静态涂覆在毛细管内壁得到一种新的气相毛细管柱,以正十二烷为溶质测得色谱柱的理论塔板数为2 337/m,与涂覆七-(2,6-O-二戊基-3-O-三氟乙酰基)-β-环糊精(DP-TFA-β-CD)的毛细管柱柱效相近;然后研究这2种毛细管柱对苯系位置异构体(如硝基甲苯、硝基氯苯、二氯苯、二甲苯和苯二甲酸二甲酯)的分离性能.结果表明,它们对邻/对、间/对取代苯系化合物表现较好的分离能力,如二氯苯的位置异构体在HP-β-CD柱上的分离因子分别为1.28和1.13,比DP-TFA-β-CD柱的分离效果好.A new capillary column was prepared by statically coating hydroxypropyl-β-cyclodextrin （ HP-β-CD） on-to inner surface of fused capillary and its theoretical plate number is measured to be 2 337 /m according to the liter-ature method, which is close to a commercial gas phase capillary column coated with heptakis-（2, 6-O-dipentyl-3-O-trifluoro acetyl）-β-cyclodextrin （ DP-TFA-β-CD） .Separations of some benzene positional isomers, namely, ni-trotoluene, chloronitrobenzene, dichlorobenzene, xylene, and dimethyl phthalate, were investigated on these two capillary columns by gas chromatography.The HP-β-CD and DP-TFA-β-CD columns show good separation abilities toward five selected analytes.Separation factors for dichlorobenzene on the HP-β-CD column are 1.28 and 1.13, respectively, which are better than the other.

关 键 词：环糊精衍生物 气相毛细管柱 位置异构体 色谱分离 

分 类 号：O657.7[理学—分析化学]