甲状腺乳头状微小癌的研究进展  

Research progress in papillary thyroid microcarcinoma

作　　者：姚庆春[1] 姜涛[1] 窦京涛[2] 

机构地区：[1]吉林油田总医院内分泌科,松原138000 [2]解放军总医院内分泌科,北京100853

出　　处：《中华老年多器官疾病杂志》2014年第10期792-795,共4页Chinese Journal of Multiple Organ Diseases in the Elderly

摘　　要：甲状腺癌是最常见的内分泌系统恶性肿瘤，其中甲状腺乳头状癌（papillary thyroid carcinoma，PTC）占80%左右。甲状腺乳头状微小癌（papillary thyroid microcarcinoma，PTMC）是指直径≤1.0cm、无论有无淋巴结转移或远处转移的PTC。近年，随着甲状腺超声技术的不断发展和广泛应用，其临床检出率呈上升趋势。一般认为PTMC的恶性程度较低，总体预后良好。但也有文献报道在诊断PTMC的同时已发现存在区域淋巴结转移或远处转移。本文就PTMC的流行病学、临床生物学以及分子生物学特点作一综述。Thyroid cancer is the most common malignancy in endocrine system,and papillarythyroid carcinoma （PTC） accounts for about 80% of thyroid cancer. Papillarythyroidmicrocarcinoma （PTMC） refers to thePTCwith the diameter less than 1.0cm, with or without lymph nodes metastases or distant metastases.In recent years, with the rapid development and wide application of ultrasonic technology,its detection rate isin a trend ofincreasing. Generally, PTMC is considered to beinlower malignancy andwithgood prognosis. However, there are still some reportsindicating PTMC have been regional or distant metastasis in lymph nodes when PTMC is diagnosed. In this paper, we reviewedtheepidemiological, clinical, biological and molecular biological characteristics of PTMC.

关 键 词：甲状腺乳头状微小癌 临床特点 BRAF基因 人类 

分 类 号：R58[医药卫生—内分泌]