格拉司琼联合地塞米松预防全麻术后恶心呕吐30例效果观察  

Clinical Effectiveness of Granisetron and Dexamethasone for Postoperative Nausea and Vomiting in Patients undergoing General Anesthesia

作　　者：汤海俊 朱玉梅[1] 张红[1] 夏晶[1] 

机构地区：[1]江苏省句容市中医院,江苏句容212400

出　　处：《中国民族民间医药》2014年第23期62-62,64,共2页Chinese Journal of Ethnomedicine and Ethnopharmacy

摘　　要：目的:对格拉司琼复合地塞米松预防全麻术后恶心呕吐的效果以及用药之间的交互作用进行观察。方法:将60例进行择期全麻手术的患者分为两组,每组30例。治疗组为格拉司琼复合地塞米松组,对照组为格拉司琼组。治疗组在麻醉诱导前分别注射格拉司琼3mg、地塞米松5mg,对照组注射格拉司琼3mg。对两组患者术后24h内的恶心、呕吐情况进行观察。结果:治疗组发生恶心呕吐的患者为1例,对照组发生恶心呕吐的患者5例。结论:格拉司琼联合地塞米松能有效预防PONV,对于患者手术的尽快恢复有一定的临床作用,而且副作用少,价格低廉,值得推广。Objective The aim of this study was to assess clinical treatment effect of Granisetron and Dexamethasone for Postop- erative Nausea and Vomiting in Patients undergoing General Anesthesia. Methods Totally 60 patients undergoing general anesthesia were randomly divided into therapy group and control group, with 30 patients in each group. Granisetron combined with dexametha- soMe was used for patients undergoing general anesthesia in the therapy group, while the control group was given granisetron only. The patients in the therapy group were injected granisetron （3rag） and dexamethasone （Smg） , before anesthesia induction. Gran- isetron （3mg） was used for patients in control group. Nausea and vomiting were recorded for 24 hours after operation. Results The treatment group patients with nausea and vomiting occurred in 1 case, the control group patients with nause and vomiting occurred in 5 cases. Conclution Granistrou combined with dexamethasone can effectively decrease the rate of PONV for patients undergoing general anesthesia.

关 键 词：格拉司琼 地塞米松 全麻 术后恶心呕吐 

分 类 号：R614.2[医药卫生—麻醉学]