合肥市3～8岁儿童麻疹风疹流行性腮腺炎抗体水平调查  

Antibodies against measles rubella and mumps among preschool children in Hefei

作　　者：刘旭祥[1,2] 王蓓[2] 王晓萍[2] 刘振武[2] 王海[2] 潘发明[1] 

机构地区：[1]安徽医科大学公共卫生学院,合肥230032 [2]合肥市疾病预防控制中心

出　　处：《中国学校卫生》2014年第10期1528-1530,共3页Chinese Journal of School Health

摘　　要：目的研究学龄前儿童麻疹、风疹、流行性腮腺炎免疫状况,为制定免疫对策提供科学依据。方法整群随机抽取合肥市427名学龄前儿童,用酶联免疫吸附试验检测麻疹、风疹、流行性腮腺炎IgG抗体水平和抗体滴度。结果 427名学龄前儿童中麻疹抗体阳性401人,阳性率为93.9%;风疹抗体阳性为385人,阳性率为90.2%;流行性腮腺炎抗体阳性332人,阳性率为77.8%。全市各县区麻疹、风疹抗体阳性率和抗体滴度差异均有统计学意义(χ2值分别为15.547,25.059,F值分别为3.989,12.319,P值均<0.05)。城市儿童麻疹抗体阳性率和抗体滴度均低于农村儿童(χ2/t值分别为5.966,4.151,P<0.05)。麻疹、风疹、流行性腮腺炎抗体几何平均滴度(GMT)随着接种针次的增加而增加,麻疹、风疹抗体阳性率随着接种针次的增加而增加(P值均<0.05)。结论合肥市麻疹有出现散发和小范围流行的可能,风疹和流行性腮腺炎学龄组出现暴发的可能性较高。Objective To understand current situation of antibodies against measles, mumps and rubella among preschool children and to provide a scientific basis for vaccination. Methods About 427 preschool children were randomized selected whose IgG antibody levels against measles, rubella, and mumps were assessed by using enzyme-linked immunosorbent assay. Results The total positive rate of measles, rubell and mumps antibody were 93.9% （401/427） , 90.2% （385/427） and 77.8% （332/ 427）, respectively. The GMT of measles, rubell and mumps antibody was 1 ： 591.7, 1 ： 285.8 and 1： 199.7, respectively. Urban children measles specific antibody positive rate and antibody titer was lower than that of rural children. Mumps GMT increased with vaccination time, measles; Rubella antibody positive rate increased with the increase of vaccination time. Conclusion There are sporadic cases and limited prevalence about measles in the future in Hefei city.

关 键 词：麻疹 风疹 流行性腮腺炎 抗体 儿童 

分 类 号：R183[医药卫生—流行病学]