MOGE(S)分类——心肌病表型-基因型对应分类方法介绍  

Introduction of MOGE( S ) Classification for Phenotype-genotype Nomenclature of Cardiomyopathy

作　　者：刘雯[1] 刘文玲[1] 

机构地区：[1]北京大学人民医院心内科,北京100044

出　　处：《心血管病学进展》2014年第6期635-639,共5页Advances in Cardiovascular Diseases

摘　　要：随着对心肌疾病认知的逐步完善,支持对心肌病采用遗传分类,这也是AHA和ESC分类的最终目的。专家建议对心肌病从5个方面进行分类,包括形态功能特性(M)、累及的器官(O)、遗传模式(G)、明确的病因(包括详细的遗传学缺陷或其他疾病原因)(E),按照ACC/AHA分级(A^D)和NYHA心功能Ⅰ~Ⅳ级进行功能状态分级(S)。功能状态的评估可由医生自行选择。这种针对5个方面进行描述的分类为MOGE(S)分类。While waiting for the complete knowledge that may eventually support a genetic classification of cardiomyopathies ,which is also the ultimate intent of the AHA and ESC classifications. The experts propose a nosology that addresses 5 simple attributes of a cardiomyo- pathic disorder, including morphofunctional characteristic （M）, organ involvement （O）, genetic or familial inheritance pattern （G）, and an explicit etiological annotation （E） with details of genetic defect or underlying disease/cause; information about the functional status （S） u- sing the ACC/AHA （A to D） stage and NYHA （ I to IV） functional classes may also be added. The addition of （S） has been left option- al, and should be used at the discretion of the physician. With the description of 5 attributes, the classification system is designated as MOGE （S）.

关 键 词：心肌病 分类 临床 基因 

分 类 号：R542.2[医药卫生—心血管疾病]