光学相干弹性成像研究现状与展望  

Research Status and Prospect of Optical Coherence Elastography

作　　者：沈熠辉 李志芳[1,2,3] 李晖[1,2,3] 

机构地区：[1]福建师范大学医学光电科学与技术教育部重点实验室,福建福州350007 [2]福建师范大学福建省光子技术重点实验室,福建福州350007 [3]福建师范大学光电与信息工程学院,福建福州350007

出　　处：《激光与光电子学进展》2014年第12期56-63,共8页Laser & Optoelectronics Progress

基　　金：国家自然科学基金(61178089;81201124);福建省科技厅重点项目(2011Y0019);卫生教育联合攻关项目(WKJ-FJ-22)

摘　　要：弹性成像技术是以软组织的杨氏模量、剪切模量、应力与应变等弹性参量为成像对象的技术。伴随着光学相干层析成像(OCT)的发展,光学相干弹性成像(OCE)由于其微米级别的分辨率,实时的图像处理以及非侵入式成像得到人们的青睐。综述了OCE的分类以及当今主流的几种OCE技术及其弹性图像重构的问题。探讨了OCE中施加机械负载方法和位移估算、应变估计的方法。OCE对检测组织临床上和病理上的机械特性拥有强大的潜力,特别是在诊断癌症,心血管疾病和眼科疾病上。总结了OCE研究和发展状况,并对其发展前景进行了展望。Elastography is a technique based on Young＇s modulus, shear modulus,stain and stress in soft tissue. With the development of optical coherent tomography （OCT）, optical coherence elastography （OCE） becomes popular because of its micron meter level resolution, real-time image processing and noninvasive imaging. The classification of OCE, several kinds of dominant OCE and elastography reconstruction are reviewed. The method of applying mechanical load and estimating displacement and strain is discussed. OCE has a great potential in detecting the clinical and pathological mechanical properties, especially in the diagnosis of cancer, cardiovascular disease and eye disease. The research development of OCE is summarized and its prospect is also discussed.

关 键 词：光学相干层析成像 弹性成像 位移 应变 

分 类 号：O439[机械工程—光学工程]