老年高血压患者血压变异性对肾功能的影响  

The relationship between blood pressure variability and renal function in aged patients with hypertension

作　　者：靳松[1] 沈干[2] 丁琪[1] 袁志华[1] 

机构地区：[1]安徽医科大学附属省立医院,安徽省立医院老年医学科,合肥230001 [2]安徽省保健委员会

出　　处：《中国临床保健杂志》2014年第6期602-604,共3页Chinese Journal of Clinical Healthcare

摘　　要：目的探讨老年人群中血压变异性与肾功能损害之间的关系。方法纳入123例老年高血压患者,计算入组患者的肾小球滤过率(GFR),以90 m L/min为临界值将其分为肾功能正常组和肾功能异常组,监测患者的24 h动态血压。结果 (1)肾功能正常组白天的收缩压变异性明显小于肾功能异常组,但是白天的平均血压肾功能正常组却显著高于肾功能异常组;(2)年龄、白天收缩压的变异性与GFR呈负相关,而全天的舒张压,白天的舒张压、平均血压,夜间的舒张压与GFR呈正相关。结论血压变异性尤其是收缩压的变异性与肾功能不全独立相关。Objective To investigate the relationship between blood pressure variability （BPV）and renal injury in elderly patients with hypertension.Methods One hundred and twenty-three patients were divided into two groups （GFR≥90 ml/min group and GFR 〈90 ml/min group）.Twenty-four hours ambulatory blood pressure monito-ring （ABPM）was performed in all patients.Results 1 .Patients in GFR≥90 ml/min group had lower day systolic BPV （SBPV）but higher day average blood pressure than patients in GFR 〈90 ml/min group;2.Correlation analysis showed positive correlation between GFR and age,day systolic BPV,and negative correlation between GFR and all day diastolic blood pressure （DBP）,day DBP,mean BP,night DBP.Conclusion BPV,especially SBPV is closely relat-ed to renal dis-function.

关 键 词：高血压 肾功能不全 肾小球滤过率 老年人 

分 类 号：R544.1[医药卫生—心血管疾病]