肺癌化疗患者肺部感染联合用药治疗的临床疗效评价  

Evaluation of clinical curative effect of drug combination therapy of lung infection in patients with lung chemotherapy

作　　者：刘怡妍 陈晨[1,2] 赵静[1,2] 

机构地区：[1]复旦大学附属肿瘤医院心肺功能科 [2]复旦大学上海医学院肿瘤学系,上海200032

出　　处：《中华医院感染学杂志》2014年第23期5833-5835,共3页Chinese Journal of Nosocomiology

基　　金：教育部高等学校博士学科点专项科研基金资助项目(20090171120070)

摘　　要：目的研究分析肺癌患者化疗后肺部感染应用痰热清注射液联合抗菌药物治疗的临床疗效,为临床治疗肺癌化疗后肺部感染提供参考依据。方法选取2011年7月-2013年7月收治的50例肺癌化疗后肺部感染患者,随机分成研究组和对照组,各25例;对照组单纯给予抗菌药物治疗,研究组在对照组基础上联合痰热清注射液治疗,对两组治疗后临床疗效等情况进行观察对比。结果治疗总有效率研究组为92.0%、对照组为72.0%,研究组总有效率显著优于对照组,差异有统计学意义(P<0.05);研究组住院时间(20.8±5.9)d,发热缓解时间(3.5±1.2)d,肺部啰音消失时间(3.7±1.1)d,咳嗽、咳痰减少时间(3.3±1.2)d;对照组住院时间(27.1±6.2)d,发热缓解时间(6.0±1.7)d,肺部啰音消失时间(4.8±1.4)d,咳嗽、咳痰减少时间(4.4±1.7)d;研究组上述指标显著低于对照组,差异有统计学意义(P<0.05)。结论痰热清注射液联合抗菌药物治疗肺癌化疗后肺部感染临床疗效显著,可迅速改善患者临床症状,缩短住院时间,提升生活质量。OBJECTIVE To investigate and analyze the clinical curative effect of Tangreqing injection combined with antibiotics in the treatment of pulmonary infection after lung cancer chemotherapy so as to provide a favorable basis for the clinical treatment. METHODS A total of 50 lung cancer cases with lung infection after chemotherapy were selected from Jul. 2007 to Jul. 2013 and randomly divided them into a study group and a control group ,each with 25 cases. The control group was given antibiotic therapy only ;the study group was given Tangreqing injection on the basis of the control group. The clinical efficacy of the two groups after the treatment were observed and com‐pared. RESULTS The total effective rate was 92. 0% in the study group ,and in the control group ,it is 72. 0%. The total effective rate of the study group was significantly higher than the control group （P〈0. 05）;The hospital stay in the study group was （20. 8 ± 5. 9 ） d ,the fever remission time was （3. 5 ± 1. 2） d ,the pulmonary riles re‐mission time was （3. 7 ± 1. 1） d ,the cough and expectoration remission time was （3. 3 ± 1. 2） d;while in the con‐trol group ,the hospital stay was （27. 1 ± 6. 2） d ,the fever remission time was（6. 0 ± 1. 7） d ,the pulmonary rales remission time was （4. 8 ± 1. 4） d ,the cough and expectoration remission time was （4. 4 ± 1. 7） d. The index in the study group was significantly lower than the control group （P〈0. 05）. CONCLUSION Tangreqing injection combined with antibiotics has remarkable curative effect in the treatment of pulmonary infection after lung cancer chemotherapy. It can rapidly improve the clinical symptoms and shorten the length of stay ,and improve quality of lif e.

关 键 词：痰热清注射液 肺癌 肺部感染 临床疗效 

分 类 号：R978.1[医药卫生—药品]