胃部分切除患者患胆石症与幽门螺杆菌感染的相关性研究  

Correlation study between partial gastrectomy patients complicated with cholelithiasis and Helicobacter pylori infection

作　　者：王建祥[1] 刘峰[1] 周锐[1] 

机构地区：[1]华中科技大学同济医学院附属普爱医院普外科,湖北武汉430033

出　　处：《中华医院感染学杂志》2014年第23期5900-5902,共3页Chinese Journal of Nosocomiology

基　　金：湖北省卫生厅基金资助项目(HW-2011B-020)

摘　　要：目的研究胃部分切除术后并发胆石症与幽门螺杆菌(Hp)感染的相关性,以期为临床治疗提供参考依据。方法选取2011年1月-2013年1月入院诊治的胃部分切除术后并发胆石症的患者64例为试验组;另选取同期入院接受其他手术后并发胆石症的患者64例为对照组;回顾性分析两组患者的临床资料,探究胃部分切除术后并发胆石症与Hp感染的相关性,采用SPSS 20.0进行统计分析。结果试验组Giemsa染色检测Hp阳性率为93.75%、对照组为48.44%;试验组Hp IgG检测Hp阳性率为82.82%、对照组为37.50%;试验组经Hp免疫组化检测Hp阳性率为62.50%、对照组为41.67%;两组差异有统计学意义(P<0.05);且胃部分切除术后残胃体或残胃底部、术后时间在3年内、术后合并反流症状易合并幽门螺杆菌感染。结论胃部分切除术后Hp感染是引起术后并发胆石症的重要危险因素,为避免胆石症的发生,需要临床工作者对胃部分切除术后的患者积极预防控制Hp感染。OBJECTIVE To study the relevancy between partial gastrectomy patients complicated with cholelithiasis and Helicobacter pylori （Hp） infection , so as to provide a reference for clinical diagnosis and treatment . METHODS A total of 64 patients who were admitted from Jan .2011 to Jan .2013 and with cholelithiasis after par‐tial gastrectomy were selected as an experimental group ;another 64 patients who were admitted in the same period and complicated with cholelithiasis after other surgeries were set as the control group .The clinical data of the two groups of patients were retrospectively analyzed to explore the relevancy between partial gastrectomy complicated with cholelithiasis and Hp infection .SPSS20 .0 was adopted for a statistic analysis .RESULTS The Hp positive rate of Giemsa staining detection was 93 .75 % in the experimental group and in the control group , it was 48 .44% .The Hp positive rate detected by IgG of the experimental group was 82 .82% ,in the control group ,it was 37 .50% . The Hp positive rate of the experimental group through immunohistochemical detection was 62 .50% ,the control group was 41 .67% .The difference was significant （P〈0 .05） .And the remaining gastric body and bottom combined with regurgitation symptom after partial gastrectomy were easy to get infected by Hp in the three years .CONCLUSION Partial gastrectomy combined with Hp infection is an important risk factor for postoperative cholelithiasis .Physicians need to actively prevent and control Hp infection from patients after partial gastrectomy to avoid cholelithiasis .

关 键 词：胃部分切除术 胆石症 幽门螺杆菌 感染 相关性 

分 类 号：R181.32[医药卫生—流行病学]