烧伤外科创面金黄色葡萄球菌感染与定植患者特征调查  

INVESTIGATION ON FEATURES OF BURN WARDS PATIENTS WITH WOUND staphylo-coccus aureus COLONIZATION AND INFECTION

作　　者：许献荣[1] 倪俊[1] 陈瑞彩[1] 孙建文[1] 顾海峰[1] 张杏梅[1] 

机构地区：[1]解放军第八五医院,上海200052

出　　处：《中国消毒学杂志》2014年第11期1193-1194,1197,共3页Chinese Journal of Disinfection

基　　金：上海市卫生局科研基金(20134489)

摘　　要：目的了解烧伤外科患者创面金黄色葡萄球菌感染与定植情况,为制定防控措施提供参考。方法通过临床观察和细菌分离鉴定,对某医院烧伤外科住院烧伤患者创面感染病原菌和临床特征进行调查。结果调查期间从该医院烧伤科患者创面分泌物标本中分离出金黄色葡萄球菌112株,其中耐甲氧西林菌株(MRSA)占77.68%。烧伤患者创面多呈现深度创面和难愈性创面,造成长时间住院,接受多种侵入性操作,常伴有基础疾病和生理指标异常,且使用抗菌药物。患者住院时间>30 d、至少有一项生理指标异常、有近期侵袭性操作是创面MRSA定植和感染的危险因素。结论烧伤外科患者创面检出MRSA主要是接触感染和定植,致创面经久不愈,应采取针对性的防控措施。Objective To investigate the Staphylococcus aureus （SA） colonization and infection status of burn wards pa- tients, so as to provide reference to prevention and control of wound infection. Methods Clinical observation, bacteria separation and identification technology were used to investigate the pathogenic bacteria and clinical features of wound infec- tion in burn wards patients. Results A total of 112 stain of SA were isolated from specimens of wound excretion from bum wards patients during investigation. 77. 68% of SA were methieillin - resistant Staphylococcus aureus （MRSA）. With deep wound or refractory wound frequently, stayed in hospital longer, received invasive procedure, underlying chronic illness or physiological indexes abnormal, antibacterial drugs used were features of the patients with wound SA isolated. Stayed in wards more than 30 days, at least one physiological indexes abnormal and recent invasive procedure were risk factors for the wound MRSA colonization and infection. Conclusion MRSA isolated from bum wards patients comes from contact infection or colonization. Wound MRSA exist delays wound healing, so some tailored measures should be very important.

关 键 词：烧伤患者 创面感染 耐甲氧西林金黄色葡萄球菌 危险因素 

分 类 号：R181.32[医药卫生—流行病学]