近红外光谱法快速鉴别市售不同厂家生产的藿胆丸  

Rapid Identification of Huodan Pills from Different Manufacturers by Near Infrared Spectroscopy

作　　者：蔡佳良[1] 姬生国[2] 

机构地区：[1]广州市医药职业学校,广州510430 [2]广东药学院中药学院,广州510006

出　　处：《中国药房》2014年第47期4458-4460,共3页China Pharmacy

基　　金：广东省科技计划项目(No.2009B030801044)

摘　　要：目的:建立快速鉴别市售不同厂家生产的藿胆丸的方法。方法:采用近红外光谱法。采集7个厂家的藿胆丸样品的近红外光谱,并用判别分析方法和聚类分析方法分别对数据进行分析。结果:聚类分析中,当类间距离为0.64时,K厂家和G厂家样品首先聚为一类,当类间距离为1.84时,其他5个厂家样品自成一类;所建立的判别分析模型错判例数为0,判别分析准确率为100%。结论:所建立的近红外光谱法可以快速、准确、无损地对不同厂家生产的藿胆丸制剂进行定性分析。OBJECTIVE ： To establish the method for rapid identification of Huodan pills from different manufacturers. METH- ODS： The near infrared spectroscopy （NIRS） was adopted. Near infrared spectrum of Huodan pills from 7 manufacturers were col- lected and analyzed by discriminative analysis and cluster analysis. RESULTS： None of erroneous judgement was found in estab- lished discriminative analysis model, and accuracy rate of discriminative analysis was 100%. In cluster analysis, when between class distance was 0.64, the samples from manufacturer K and G were classified as same class firstly; when between class distance was 1.84, the samples from other 5 manufacturers were classified as same class. CONCLUSIONS： NIRS method is rapid, accurate and nondestructive, and can be used for qualitative analysis of Huodan pills from different manufacturers.

关 键 词：近红外光谱法 藿胆丸 判别分析 聚类分析 

分 类 号：R284.1[医药卫生—中药学]