实时荧光PCR检测妊妇B族溶血性链球菌及临床意义  

作　　者：杜琼[1] 刘祥琴[1] 施婷[2] 龙娟[1] 马文娅[1] 黄果[1] 张欣[1] 

机构地区：[1]四川省人民医院检验科,四川成都610072 [2]泸州医学院2009级医学检验系实习生,四川泸州646000

出　　处：《特别健康（下）》2014年第10期25-25,共1页SPECIAL HEALTH

摘　　要：目的：利用实时荧光PCR的方法检测孕产妇B族溶血性链球菌（group B streptococcus，GBS），了解其带菌情况及临床意义。方法采集1008例孕产妇阴道下1／3分泌物及肛周分泌物应用实时荧光PCR的方法进行GBS的核酸检测并观察阳性者对母儿的影响。结果GBS的检出率为5．4％（54／1008）；GBS阳性孕妇的早产率为27．8％（15／54），流产率为16．7％（9／54），胎膜早破率为26．0％（14／54），胎儿窘迫的发生率为24.0％（13／54）；结论GBS带菌者增加了早产、流产、胎膜早破、胎儿窘迫的发生率，对母儿结局造成不良影响。Objective To investigate the group B streptococcus （GBS） colonization rate in pregnancy women with real - time fluorescence PCR technique and it＇ s clinical significance. Methods Pick up the vaginal secretions and anal secretions in the 1008 cases to test GBS through real -time PCR, and observe the infection on pregnancy women and their neonates. Results The GBS colonization rate of the pregnancy women was 5.4% （54/1008）. The preterm birth rate of the pregnancy women with GBS - DNA positive was 27.8% （15/54）. The Abortion rate of the pregnancy women with GBS - DNA positive was 16.7% （9/54）. Conclusions pregnancy women with GBS can increase the incidences of preterm birth, abortion, fetal distress, premature rupture of membranes.

关 键 词：GBS 实时荧光PCR 

分 类 号：R71[医药卫生—妇产科学]