输精管结扎对中老年前列腺症状和患前列腺癌风险的影响  

Effects of vasectomy on prostate symptoms and the risk of prostate cancer in middle-aged and elderly

作　　者：官黄涛[1] 商进[1] 赵凯[1] 陈耀平[1] 夏伟[1,2] 李红钢[1,2] 章慧平[1,2] 商学军[3] 谷翊群[4] 熊承良[1,2] 

机构地区：[1]华中科技大学同济医学院计划生育研究所/生殖医学中心,湖北武汉430030 [2]武汉同济生殖医学专科医院,湖北武汉430030 [3]南京军区南京总医院,江苏南京210002 [4]国家人口计生委科学技术研究所,北京100081

出　　处：《中国计划生育和妇产科》2014年第9期9-11,15,共4页Chinese Journal of Family Planning & Gynecotokology

基　　金："十二五"国家科技支撑计划项目(项目编号:2012BAI32B03)

摘　　要：目的探讨输精管结扎对中老年前列腺症状和患前列腺癌风险的影响。方法调查北京、湖北、江苏309名已行输精管结扎的中老年人,同时按1∶2比例选取618名年龄匹配的未结扎中老年人作为对照,以填写调查问卷方式计算国际前列腺症状评分表(international prostate symptom score,IPSS)评分,留取外周血进行前列腺特异性抗原(prostate specific antigen,PSA)和游离PSA检测,比较两组间差异。结果在所调查的人群中,经矫正教育程度等因素后,输精管结扎组和非结扎组之间IPSS评分、PSA水平、游离PSA和游离PSA百分比比较差异无统计学意义(P>0.05)。结论输精管结扎术不影响前列腺的症状,也不提高前列腺癌的风险。Objective To explore the effects of vasectomy on prostate symptoms and risk of prostate cancer in middle- aged and elderly. Methods A survey of 309 cases of middle- aged and elderly with vasectomy in Beijing,Hubei,Jiangsu was performed. 618age- matched non- vasectomy middle- aged and elderly were selected as a control with a proportion of 1： 2. The international prostate symptom score（ IPSS） of two groups were calculated by questionnaires,the peripheral blood samples were collected to detect prostate specific antigen（ PSA） and free PSA. The differences between the two groups were compared. Results In the investigated population,IPSS score,level of PSA,free PSA and free PSA percentage between vasectomy group and non- vasectomy group had no significant difference after adjusted education factors. Conclusion Vasectomy does not affect the prostate symptoms or elevate the risk of prostate cancer.

关 键 词：输精管结扎 前列腺症状 国际前列腺症状评分表 前列腺特异性抗原 

分 类 号：R699[医药卫生—泌尿科学]