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机构地区:[1]南京军区南京总医院 [2]南京大学医学院临床学院国家肾脏疾病临床医学研究中心全军肾脏病研究所,南京210002
出 处:《中国实用内科杂志》2014年第12期1144-1146,共3页Chinese Journal of Practical Internal Medicine
摘 要:随着人口老龄化加剧,预计至2050年全球65岁以上的老年人将达到15亿。70岁以上老年人1/3-1/2患有慢性肾脏病(CKD),老年CKD已成为中国面临的重要公共卫生挑战。近10年来,老年终末期肾脏疾病(ESRD)患者比例显著增加,影响老年CKD患者进展为ESRD的危险因素有:蛋白尿、高血压、糖尿病、高血脂和不良饮食习惯等。然而,大多数老年CKD患者在进入ESRD之前死于心血管疾病、感染和脑血管病。该文简要介绍延缓老年CKD进展的综合治疗,以期为延缓老年CKD病情进展提供指导。The global population is progressively aging,to the extent that over 1. 5 billion people worldwide will be aged 65 years or more by 2050. Chronic kidney disease( CKD) in the elderly has become a major public health problem in China with approximately one third to one half of the individuals older than 70 years have CKD. Rates of treated end-stage renal disease( ESRD) among the elderly have been rising dramatically over the last decade. Most of older individuals with CKD die from cardiovascular diseases,infections and cerebrovascular diseases before reaching ESRD. Proteinuria,hypertension,diabetes,hyperlipidemia,and diet are strong risk factors for progression from CKD to ESRD. In this review,we will discuss comprehensive treatment strategy in preventing and slowing progression of CKD in elderly patients concerning the above risk factors.
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