重症颅脑损伤患者肺部感染病原菌分布  

Distribution of pathogens for pulmonary infection in patients with severe brain injury

作　　者：舒宇峰 吴陈英 钟玉平 叶碎林[2] 

机构地区：[1]浙江省庆元县人民医院神经外科,浙江庆元县323800 [2]丽水市人民医院神经外科,浙江丽水323000

出　　处：《中华医院感染学杂志》2014年第24期6158-6159,6173,共3页Chinese Journal of Nosocomiology

基　　金：浙江省医药卫生科技基金资助项目(2010KYB134)

摘　　要：目的分析重症颅脑损伤并发肺部感染病原菌的分布,观察比较早期物理治疗的效果,寻求一种更为有效的辅助治疗方法,以提高有效率。方法对2011-2013年县市各医院收治的105例重症颅脑损伤合并肺部感染患者病原菌的分布进行调查研究,将所调查患者随机分为试验组55例、对照组50例,对其早期物理治疗的疗效进行观察对比,采用SPSS13.0进行统计分析。结果痰液培养出的病原菌254株,其中革兰阴性菌203株占79.92%,革兰阳性菌51株占20.08%;在治疗效果方面,试验组的血氧饱和度和血氧分压均比对照组患者高,而对照组的CSS评分(20.83±2.19)分、呼吸恢复时间(2.41±0.35)d等均显著高于试验组。结论加强对可能引起患者肺部感染的病原菌的控制,以及早期对患者正确及时,快速有效的物理治疗干预,将很大程度上提高了患者治疗的有效率,使患者早日康复。OBJECTIVE To analyze the distribution of pathogens for severe traumatic brain injury complicated by pulmonary infection ,observe and compare the effect of early physical therapies to seek a more effective adjuvant therapy to improve efficacy .METHODS Distribution of pathogens for patients with severe traumatic brain injury complicated by pulmonary infection admitted to hospitals in the city and counties during the year 2011-2013 were investigated .The investigated patients were randomly divided into the experimental group （55 cases） and the con‐trol group （50 cases ） . The efficacy of early physical therapies were observed and compared . The software SPSS13 .0 was used for statistical analysis .RESULTS Totally 254 pathogens were detected by sputum culture in‐cluding 51 gram‐positive bacteria （20 .08% ） and 203 gram‐negative bacteria （79 .92% ） .For the treatment effect , the oxygen saturation and the blood oxygen pressure were higher in the experimental group than in the control group ,and the CSS score and the breathing recovery time were significantly higher in the control group （20 .83 ± 2 .19） points ,（2 .41 ± 0 .35） d than in the experimental group .CONCLUSION Strengthening control of possible pathogens causing pulmonary infection and early ,timely ,rapid and effective physical therapy intervention will greatly improve the efficacy of treatment and achieve early recovery .

关 键 词：重症脑颅损伤 肺部感染 病原菌 耐药性 

分 类 号：R563[医药卫生—呼吸系统]