肾病综合症治疗进展及管理  

The recent advances in the treatment of nephrotic syndrome and management

作　　者：吴宝珍 

机构地区：[1]广西宾阳县人民医院儿科,广西宾阳530405

出　　处：《临床医药文献电子杂志》2014年第9期873-873,876,共2页Electronic Journal of Clinical Medical Literature

摘　　要：肾病综合征是儿童常见的慢性疾病,据统计儿童年发病率约为2/100 000~4/100 000,患病率为16/100 000,该病可发生在任何年龄,但多发在2~6岁,男孩多见,男女比例3：2,近年来该病呈逐渐增多趋势。目前肾病综合症治疗进展及长期管理中,很多儿科医师和患儿家长为减少肾病综合症复发及对并发症的治疗而共同努力。肾病综合症是一组由多种原因引起的肾小球基底膜通透性增加,导致血浆内大量蛋白质从尿中丢失的临床综合征,以大量蛋白尿、低蛋白血症、高脂血症和明显水肿为临床表现。Nephrotic syndrome is a common chronic disease in children, according to statistics, children＇s annual incidence of about 2/100 000-4/100 000, prevalence was 16/100 000, the disease can occur at any age, but happens in 2- 6 years of age, the boy see more, the male to female ratio 3：2, in recent years an increasing trend of the disease. The current advances in the treatment of nephrotic syndrome and long-term management, many pediatricians and parents to reduce the recurrence of nephrotic syndrome and treatment of complications and work together. Nephrotic syndrome is a group from a number of causes increased glomerular basement membrane permeability, results in a large amounts of protein in the urine loss in the plasma of clinical syndrome, with a large amount of proteinuria, hypoalbuminemia, hyperlipidemia and edema of clinical manifestations.

关 键 词：肾病综合症 尿蛋白 激素抵抗 高脂血症 泼尼松 左旋咪唑 环磷酸胺 肾静脉血栓 

分 类 号：R256.5[医药卫生—中医内科学]