临床肺炎克雷伯菌的连续性耐药监测分析  

Continuous drug-resistant monitoring analysis of pneumonia klebsiella bacteria from clinic

作　　者：蔡静 李科[2] 

机构地区：[1]重庆市璧山县中医院,402760 [2]重庆市急救医疗中心,400014

出　　处：《检验医学与临床》2014年第A02期190-192,共3页Laboratory Medicine and Clinic

摘　　要：目的了解该院2011～2013年肺炎克雷伯菌（KPN）的临床分布特征及对常用抗菌药物的耐药特点，指导临床合理使用抗菌药物。方法采用WHONET5.6对219株KPN的标本来源、科室分布及耐药性等进行统计分析。结果2011～2013年标本检出率和耐药率均呈逐年上升趋势，检出产超广谱β-内酰胺酶（ESBLs）菌株58株，检出率为26.5％；细菌在呼吸道标本（痰、咽拭子）中的分离率最高，其科室分布以消化内科为主。结论KPN的耐药性呈逐年上升趋势。Objective to understand the inclinical distribution characteristics and characteristics of drug resist- ance to commonly used antimicrobial agents in pneumonia klebsiella bacteria（KPN） of this hospital, from 2011 to 2013,so as to guide the clinical use of antimicrobial agents rationally. Methods to analyse the specimen source, de- partment distribution and drug resistance of 219 KPN strains by WHONETS. 6. Results the detection rate and re- sistance are in rising trend year by year in 3 years from 2011 to 2013,58 strains produce ultra broad spectrum beta lactamase ESBLs strains were checked out, detection rate is 26.5%;the separation rate of the bacteria in respiratory tract specimens （phlegm,throat swab） is the highest, the distribution department is given priority to with digestive diseases. Conclusion there is an upward trend in the drug resistance of KPN.

关 键 词：肺炎克雷伯菌 临床分布 耐药率 

分 类 号：R446.5[医药卫生—诊断学]