糖尿病足溃疡感染的踝肱指数评价和抗菌药物治疗  

Infected diabetic foot ulcers ankle-brachial index evaluation and antibiotic therapy

作　　者：陈菊萍[1] 罗晓红[1] 周琳[1] 杨玲[1] 郑超[1] 

机构地区：[1]上海市浦东新区浦南医院内分泌科,200125

出　　处：《检验医学与临床》2014年第A02期225-227,共3页Laboratory Medicine and Clinic

基　　金：浦东社发局科题（PW200012）;浦东新区浦南医院特色专科建设项目（PN2012TSZB3）.

摘　　要：目的探讨踝肱指数（ABI）对糖尿病足溃疡感染的评价作用，总结抗菌药物效果，以期提高临床治疗水平。方法选取2010年4月至2013年4月85例糖尿病足溃疡感染患者为研究对象，通过多普勒血流探测仪观察患者在足背动脉、胫后动脉和肱动脉的血压值，并结合血压水平计算出ABI值，ABI≤0.9为降低组，ABl0.9～1.4为正常组，比较两组在血压等方面变化情况，并观察感染程度和预后相关指标情况。结果两组在冠心病、脑血管病和周围血管病变一般合并疾病、BMI、SBP、DBP、HbAlC、TC、TG、HDL-C、LDL-C、病程上比较差异有统计学意义（P〈0.05）；且糖尿病足溃疡感染随着病情的加重，在住院天数、治疗费用、愈合时间、愈合情况、截肢和死亡例数上变化也逐渐升高，呈正相关。结论ABI可作为糖尿病足溃疡感染的前兆，早期抗菌药物治疗预后较为理想。Objective To investigate the ankle-brachial index （ABI） infected diabetic foot ulcers evaluation role,summed up the effect of antimicrobial drugs in order to improve the level of clinical treatment. Methods April 2010 April 2013 85 cases of infected diabetic foot ulcers in patients for the study,observed by Doppler flow detector in patients with dorsal artery, posterior tibial artery and brachial artery blood pressure values, combined with ABI blood pressure levels calculated value, ABIc0.9 reduce group, ABI 0.9-1.4 for the control group were compared changes in blood pressure, etc. , and to observe the extent of infection and prognostic indicators. Results The two groups in coronary heart disease, cerebrovascular disease and peripheral vascular disease in general comorbidities in BMI,SBP,DBP,HbAlc,TC,TG,HDL-C,LDL-C,are more significant differences （P〈0.05） ; diabetic foot ulcers and infection as the disease worsens, the number of days of hospitalization, cost of treatment, healing, healing, ampu- tation and death on changes in the number of cases has gradually increased,a positive correlation. Conclusion ABI in- fected diabetic foot ulcers can be used as a precursor, early antibiotic treatment and prognosis is better.

关 键 词：糖尿病足溃疡 感染 踝肱指数 抗菌药物 

分 类 号：R587.2[医药卫生—内分泌]