扶正消瘤汤结合紫杉醇辅助治疗晚期卵巢癌  

Fuzheng Xiaoliu Decoction Combined with Paclitaxel in Treating Patients with Advanced Ovarian Cancer

作　　者：陈志刚[1] 卢宏达[1] 唐求[1] 

机构地区：[1]武汉市中心医院,武汉430014

出　　处：《中国实验方剂学杂志》2014年第24期214-216,共3页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：目的:探讨扶正消瘤汤结合紫杉醇辅助治疗晚期卵巢癌的临床效果。方法:77例晚期卵巢癌患者,根据其入院时间(单、双日)分为两组,两组均采用肿瘤减灭术联合化疗治疗,术前对照组采用紫杉醇方案治疗;治疗组采用扶正消瘤汤联合紫杉醇方案治疗,分析比对两组患者临床症状缓解情况、治疗前后肿瘤变化情况及术后不良反应发生情况。结果:本次研究中,治疗组完全缓解(CR)11例,部分缓解(PR)19例,稳定(SD)9例,治疗总有效率为69.8%,高于对照组(治疗总有效率为44.1%)(P<0.05);治疗组手术时间(215.34±32.76)min,腹水量为(678.35±32.32)m L,失血量为(502.89±118.53)m L,少于对照组(P<0.05);治疗组治疗后不良反应发生率为44.19%和对照组(58.82%)相比差异不显著。结论:对晚期卵巢癌患者采用扶正消瘤汤联合紫杉醇方案进行辅助治疗疗效确切,值得推广使用。Objective：To investigate the clinical effect of Liqi Qingre Fang by jejunal injection in combination with conventional symptomatic and supportive intervention in treating acute pancreatitis （AP）.Method：Eighty patients with AP accorded with the inclusion criteria were randomly divided into two groups of 40 patients each.The patients in both groups received conventional symptomatic and supportive intervention and the patients in observation group added Liqi Qingre Fang by jejunal injection.The curative efficacy,relevant clinical indices and inflammatory factors were observed and compared.Result：The patients in observation group had a total therapeutic ratio of 92.5%,which was statistically higher than that of 70.0% in the control group （P 〈0.05）.The disappearance time of abdominal pain,vomiting,fever,jaundice and the recovery time of serum amylase in the observation group were shorter than those in control group （P 〈 0.05）.After the treatment,inflammatory factors of interleukins （IL）-6,IL-8,tumor necrosis factor alpha （TNF-α） and high-sensitivity C-reactive protein （Hs-CRP） in the observation group were statistically lower than those in the control group （P 〈0.05）.Conclusion：The effect of using Liqi Qingre Fang by jejunal injection in combination with conventional symptomatic and supportive intervention is reliable in treating AP.It could increase the toal therapeutic ratio,improve relevant indices and alleviate inflammatory reaction,which is worthy to be applied widely in clinic.

关 键 词：扶正消瘤汤 紫杉醇 晚期卵巢癌 

分 类 号：R287.6[医药卫生—中药学]