原子吸收分光光度法测定小儿咳喘灵口服液中微量钙  

Determination of Trace Ca in Child Kechuanling Oral Liquid by Atomic Absorption Spectrophotometer

作　　者：李洪斌 吕紫璇 陈健 

机构地区：[1]重庆市涪陵食品药品检验所,重庆408000

出　　处：《中国药业》2014年第24期80-81,共2页China Pharmaceuticals

摘　　要：目的建立测定小儿咳喘灵口服液中微量钙含量的方法。方法采用Shimadzu AA-6800型原子吸收分光光度计,检测波长为422.7 nm,HNO3-H2O2（9∶1）或微波消解样品。结果钙离子质量浓度在0.5-5.0μg/m L范围内与吸光度呈良好的线性关系,r=0.9998;方法回收率分别为99.00%和99.47%,RSD分别为0.76%和0.42%（n=6）。结论所建立的方法简便、快捷,结果准确,重复性好,可应用于小儿咳喘灵口服液的质量控制。Objective To establish a atomic absorption spectrophotometry（AAS） method for determining the trace Ca content in Child Kechuanling Oral Liquid. Methods The Shimadzu AA- 6800 AAS was adopted for conducting the detection at the wavelength of422. 7 nm. The samples were digested by HNO3- H2O2（9 ∶ 1） or microwave. Results The mass concentration of Ca ion in the range of0. 5- 5. 0 μg/m L had a good linearity with the absorbance（r = 0. 9998）; the recovery rates（n = 6） were 99. 00% and 99. 47% respectively,RSD were 0. 76%（n = 6） and 0. 42%（n = 6） respectively. Conclusion The established method is simple,fast and accurate in the detection results with good repeatability,which can be used for the quality control of Child Kechuanling Oral Liquid.

关 键 词：小儿咳喘灵口服液 钙 原子吸收分光光度法 

分 类 号：R284.1[医药卫生—中药学] R286.0[医药卫生—中医学]