组织胶注射治疗胃底静脉曲张破裂出血安全性及疗效分析  

Analysis of efficacy and safety of tissue adhesive injection in treatment of gastric fundus variceal bleeding

作　　者：陈虹彬[1] 汤善宏[1] 秦建平[1] 乔丽娟[1] 倪阵[1] 刘炼炼[1] 徐辉[1] 蒋明德[1] 

机构地区：[1]成都军区总医院消化内科,成都610083

出　　处：《西南国防医药》2014年第12期1294-1297,共4页Medical Journal of National Defending Forces in Southwest China

基　　金：四川省卫生厅计划课题(120572)

摘　　要：目的探讨内镜下组织胶注射急诊治疗门静脉高压导致胃静脉曲张破裂出血的安全性及疗效。方法 64例门静脉高压胃底静脉曲张急性出血患者行内镜下组织胶注射治疗,观察分析即时止血率、曲张清除率、并发症及其影响因素。结果即时止血率为100%(65/65),术中、术后均无严重并发症出现。术后6个月曲张静脉完全消失率为30.8%(20/65),基本消失率为41.5%(27/65),部分消失率为26.2%(17/65),无效率为1.5%(1/65)。GEV1与IGV1型患者疗效显著优于GEV2型(P<0.05)。结论经内镜下注射组织胶急诊治疗门静脉高压胃底静脉曲张破裂出血止血效果好,再出血发生率低,疗效确切。Objective To explore the efficacy and safety of endoscopic tissue adhesive injection in emergent treatment of gastric fundus variceal bleeding caused by portal hypertension. Methods Total 64 patients with gastric fundus variceal bleeding caused by portal hypertension were treated with endoscopic tissue adhesive injection, and the immediate hemostasis rate, varix clearance rate, complications and the affecting factors were observed and analyzed. Results The immediate hemostasis rate was 100% （65/65）, and there were not any serious complications during and after the operation. After six months, the complete disaPPearance rate of varix was30.8% （20/65） ,the basic disappearance rate was 41.5% （ 27/65 ） , the partial disappearance rate was 26.2% （ 17/65 ） , and the inefficiency rate was 1.5% （1/65）. The efficacy of GEV1 and IGV1 type patients was significantly better than that of CEV2 type patients （ P 〈 0.05 ）. Conclusion With low rebleeding rate, endoscopic tissue adhesive injection in emergent treatment of gastric fundus variceal bleeding caused by portal hypertension has really good curative effects.

关 键 词：胃静脉曲张 组织胶 急诊 出血 

分 类 号：R657.31[医药卫生—外科学]