离子液体中Sc(OTf)_3催化下苯并[f]喹啉-1,2-二羧酸酯的合成  

Synthesis of benzo[f]quinoline-1,2-dicarboxylate catalyzed by Sc(OTf)_3 in ionic liquids

作　　者：张梅梅[1] 马宁[1] 魏志文[1] 王香善[1] 

机构地区：[1]江苏师范大学江苏省药用植物生物技术重点实验室,江苏徐州221116

出　　处：《江苏师范大学学报（自然科学版）》2014年第4期65-69,共5页Journal of Jiangsu Normal University：Natural Science Edition

基　　金：江苏省药用植物生物技术重点实验室开放课题(KLBMP1303)

摘　　要：在离子液体中,以芳醛、2-萘胺和丁炔二酸酯为原料,在Sc(OTf)3催化下,通过Povarov反应,一步合成了3-芳基苯并[f]喹啉-1,2-二羧酸酯衍生物.产物结构均经红外、氢谱和高分辨质谱确定.与其它方法相比,该方法具有反应条件温和、产率较高和环境友好等优点.A green method for the synthesis of 3-arylbenzo[f]quinoline-1,2-dicarboxylate derivatives is reported by a Povarov reaction of aromatic aldehyde,naphthalen-2-amine and but-2-ynedioate catalyzed by Sc（OTf）3 in ionic liq-uids.All the structures of the products were characterized by IR,1 HNMR and HRMS.Compared to the previous method,this procedure has the advantages of mild reaction condition,high yield and environmentally benign.

关 键 词：苯并[f]喹啉 Povarov 反应 Sc(OTf)3 芳醛 2-萘胺 丁炔二酸酯 离子液体 

分 类 号：O626.3[理学—有机化学]