胸液P-选择素检测对结核性与恶性胸腔积液鉴别意义的探讨  

Significance of detecting P-selectin of pleural effusion in differentiating tuberculous and malignant pleural effusions

作　　者：赵云峰[1] 王英年[1] 高岱清[1] 张春玲[1] 马学真[1] 吴学玲[1] 刘加洪[1] 

机构地区：[1]青岛大学医学院第二附院,青岛266042

出　　处：《中国防痨杂志》2002年第4期200-202,共3页Chinese Journal of Antituberculosis

摘　　要：目的　检测结核性及恶性胸腔积液患者胸液P -选择素水平 ,探讨其对鉴别良恶性疾病的意义。方法　采用酶联免疫吸附法 (ELISA法 )检测 48例结核性胸液及 5 0例恶性胸液P -选择素水平。结果　恶性胸液P -选择素水平 (1 8.76± 8.45 μg/L)明显高于结核性胸液P -选择素 (7.43±5 .3 2 μg/L) (P <0 .0 1 )。结论　测定胸液PObjective To explore the clinical significance of detecting P-selectin of pleural effusions in differentiating tuberculous and malignant diseases.Methods To detect the content of P-selectin in centrifuged supernatant of 48 cases with tuberculous pleural effusions and 50 cases with malignant pleural effusions by ELISA method.Results P-selectin of malignant pleural effusions (18.76±8.45μg/L) was distinctly higher than that of tuberculous pleural effusions (7.43±5.32μg/L) ( P <0.01).Conclusion Detecting P-selectin of pleural effusion might be helpful for differentiating tuberculous and malignant diseases.

关 键 词：P-选择素 胸腔积液 酶联免疫吸附试验 

分 类 号：R446.6[医药卫生—诊断学]